Evidence map›Paper›PMID 28992268›Full record

Trial reportSocial cognitive and affective neuroscience2017

Propranolol reduces reference-dependence in intertemporal choice.

Karolina M Lempert, Sandra F Lackovic, Russell H Tobe, Paul W Glimcher, Elizabeth A Phelps

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Social cognitive and affective neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Intertemporal choice reflects value comparison rather than self-control: insights from confidence judgements.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  6. Decision neuroscience and neuroeconomics: Recent progress and ongoing challenges.Wiley interdisciplinary reviews. Cognitive science · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Karolina M LempertDepartment of Psychology, New York University, New York, NY 10003, USA.
Sandra F LackovicDepartment of Psychology, New York University, New York, NY 10003, USA.
Russell H TobeNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA.
Paul W GlimcherCenter for Neural Science, New York University, New York, NY 10003, USA.
Elizabeth A PhelpsDepartment of Psychology, New York University, New York, NY 10003, USA.
New York University · USNathan Kline Institute for Psychiatric Research · US

Funding

Emotions and Choice: Mechanisms of Behavior ChangeR01AG039283 · NIA · NEW YORK UNIVERSITY · PI PHELPS, ELIZABETH ANYA · 2010 to 2014
$2.1M
NIA NIH HHS R01 AG039283
6 · The paper itself

Abstract

In intertemporal choices between immediate and delayed rewards, people tend to prefer immediate rewards, often even when the delayed reward is larger. This is known as temporal discounting. It has been proposed that this tendency emerges because immediate rewards are more emotionally arousing than delayed rewards. However, in our previous research, we found no evidence for this but instead found that arousal responses (indexed with pupil dilation) in intertemporal choice are context-dependent. Specifically, arousal tracks the subjective value of the more variable reward option in the paradigm, whether it is immediate or delayed. Nevertheless, people tend to choose the less variable option in the choice task. In other words, their choices are reference-dependent and depend on variance in their recent history of offers. This suggests that there may be a causal relationship between reference-dependent choice and arousal, which we investigate here by reducing arousal pharmacologically using propranolol. Here, we show that propranolol reduces reference-dependence, leading to choices that are less influenced by recent history and more internally consistent.

Indexed as

Adrenergic beta-AntagonistsAdultArousalChoice BehaviorDelay DiscountingDouble-Blind MethodFemaleHumansMalePropranololPsychomotor PerformanceReflex, PupillaryYoung AdultAdrenergic beta-AntagonistsPropranololemotional arousalintertemporal choicepropranololpupil dilationtemporal discounting

Identifiers

PMID28992268
PMCPMC5737445
OpenAlexW2730534029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.