Evidence map›Paper›PMID 28991949›Full record

Trial reportJournal of hospital medicine2017

Post-Intensive Care Unit Psychiatric Comorbidity and Quality of Life.

Sophia Wang, Chris Mosher, Anthony J Perkins, Sujuan Gao, Sue Lasiter, Sikandar Khan, Malaz Boustani, Babar Khan

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Journal of hospital medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Risk factors for dementia in older intensive care unit (ICU) survivors.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  5. Review
  6. Delirium, depression, and long-term cognition.International psychogeriatrics · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Aging and Post-Intensive Care Syndrome: A Critical Need for Geriatric Psychiatry.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Sophia WangDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA. sophwang@iupui.edu.
Chris MosherDepartment of Internal Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Anthony J PerkinsCenter of Health Innovation and Implementation Science, Center for Translational Science and Innovation, Indianapolis, Indiana, USA.
Sujuan GaoDepartment of Biostatistics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Sue LasiterUniversity of Missouri-Kansas City School of Nursing and Health Studies, Kansas City, Missouri, USA.
Sikandar KhanDivision of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Malaz BoustaniSandra Eskenazi Center for Brain Care Innovation, Eskenazi Hospital, Indianapolis, Indiana, USA.
Babar Khan
Indiana University School of MedicineIndiana University – Purdue University Indianapolis · USCenter for Innovation · USEskenazi Health Foundation · USUniversity of Missouri–Kansas City · US

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3M
READI-SET-GO: Researching Efficient Approaches to Delirium Identification - Sustaining Effective Translation to create Gero-friendly OrganizationsR01AG030618 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI DONNA Marie FICK, EDWARD R MARCANTONIO · 2008 to 2026
$7.9M
IU Training Program in Molecular Physiology and Clinical Mechanisms of Lung DiseaseT32HL091816 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Erick Forno, Roberto F. Machado · 2009 to 2026
$4.3M
Mobile Critical Care Recovery Program (m-CCRP) for Acute Respiratory Failure (ARF) SurvivorsR01HL131730 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI KHAN, BABAR A · 2017 to 2021
$3.2M
Longitudinal interactive vascular exposure and Alzheimer's DiseaseR01AG045350 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI GAO, SUJUAN · 2014 to 2016
$925k
Delirium Biomarkers in the Intensive Care UnitK23AG043476 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI KHAN, BABAR A · 2012 to 2016
$629k
NHLBI NIH HHS R01 HL131730NHLBI NIH HHS T32 HL091816NIA NIH HHS K23 AG043476NIA NIH HHS P30 AG010133NIA NIH HHS R01 AG030618NIA NIH HHS R01 AG045350
6 · The paper itself

Abstract

The prevalence of psychiatric symptoms ranges from 17% to 44% in intensive care unit (ICU) survivors. The relationship between the comorbidity of psychiatric symptoms and quality of life (QoL) in ICU survivors has not been carefully examined. This study examined the relationship between psychiatric comorbidities and QoL in 58 survivors of ICU delirium. Patients completed 3 psychiatric screens at 3 months after discharge from the hospital, including the Patient Health Questionnaire-9 (PHQ-9) for depression, the Generalized Anxiety Disorder-7 (GAD-7) questionnaire for anxiety, and the Post-Traumatic Stress Syndrome (PTSS- 10) questionnaire for posttraumatic stress disorder. Patients with 3 positive screens (PHQ-9 = 10; GAD-7 = 10; and PTSS-10 > 35) comprised the high psychiatric comorbidity group. Patients with 1 to 2 positive screens were labeled the low to moderate (low-moderate) psychiatric comorbidity group. Patients with 3 negative screens were labeled the no psychiatric morbidity group. Thirty-one percent of patients met the criteria for high psychiatric comorbidity. After adjusting for age, gender, Charlson Comorbidity Index, discharge status, and prior history of depression and anxiety, patients who had high psychiatric comorbidity were more likely to have a poorer QoL compared with the low-moderate comorbidity and no morbidity groups, as measured by a lower EuroQol 5 dimensions questionnaire 3-level Index (no, 0.69 ± 0.25; low-moderate, 0.70 ± 0.19; high, 0.48 ± 0.24; P = 0.017). Future studies should confirm these findings and examine whether survivors of ICU delirium with high psychiatric comorbidity have different treatment needs from survivors with lower psychiatric comorbidity.

Indexed as

ComorbidityIntensive Care UnitsQuality of LifeCritical CareFemaleHumansMaleMental DisordersMiddle AgedPatient DischargeRespiratory Distress SyndromeSurveys and Questionnaires

Identifiers

PMID28991949
PMCPMC6160262
OpenAlexW2753375518

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.