Evidence map›Paper›PMID 28991885›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Predictors of HIV, HIV Risk Perception, and HIV Worry Among Adolescent Girls and Young Women in Lilongwe, Malawi.

Joan T Price, Nora E Rosenberg, Dhrutika Vansia, Twambilile Phanga, Nivedita L Bhushan, Bertha Maseko, Savvy K Brar, Mina C Hosseinipour, Jennifer H Tang, Linda-Gail Bekker and 1 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05516602 (Improving HIV Prevention Among Adolescent Girls and Young Women), which is not on this map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05516602 nacompletednot on this mapstarted 2023, after this paper: background citation

Improving HIV Prevention Among Adolescent Girls and Young Women (AGYW) in Uganda

TypeinterventionalSponsorMRC/UVRI and LSHTM Uganda Research UnitRan2023 to 2024Enrolled394ConditionsHIV-1-infectionArmsPeer Support
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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  11. Associations Between Substance Use, Sexual Violence, Mental Distress, and Sexual HIV Risk Behaviors Among Adolescent Girls and Young Women in Lesotho.AIDS education and prevention : official publication of the International Society for AIDS Education · 2025
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  20. Personal factors influencing female students' condom use at a higher education institution.African journal of primary health care & family medicine · 2024
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Joan T PriceDivision of Global Women's Health, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Nora E RosenbergDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Dhrutika VansiaUNC Project Malawi, Lilongwe, Malawi.
Twambilile PhangaUNC Project Malawi, Lilongwe, Malawi.
Nivedita L BhushanUNC Project Malawi, Lilongwe, Malawi.
Bertha MasekoUNC Project Malawi, Lilongwe, Malawi.
Savvy K BrarUNC Project Malawi, Lilongwe, Malawi.
Mina C HosseinipourUNC Project Malawi, Lilongwe, Malawi.
Jennifer H TangDivision of Global Women's Health, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Linda-Gail BekkerDesmond Tutu HIV Centre, Cape Town, South Africa.
Audrey PettiforDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
University of North Carolina at Chapel Hill · USDesmond Tutu HIV Foundation · ZA

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
UNC Global Women’s Health FellowshipT32HD075731 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2013 to 2024
$2.4M
Developing and Assessing a Male Engagement Intervention for Option B+ in MalawiR00MH104154 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROSENBERG, NORA · 2017 to 2019
$746k
A Career Development Award in HIV-Associated Preterm Birth and its PreventionK01TW010857 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PRICE, JOAN · 2017 to 2021
$682k
Developing and Assessing a Male Engagement Intervention for Option B+ in MalawiK99MH104154 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROSENBERG, NORA · 2015 to 2016
$168k
FIC NIH HHS K01 TW010857FIC NIH HHS R25 TW009340NIAID NIH HHS P30 AI050410NICHD NIH HHS P2C HD050924NICHD NIH HHS T32 HD075731NIMH NIH HHS K99 MH104154NIMH NIH HHS R00 MH104154
6 · The paper itself

Abstract

backgroundAdolescent girls and young women (AGYW) in sub-Saharan Africa have high HIV prevalence and incidence. We sought to understand which HIV risk factors individually and in combination contribute to risk, and whether these factors are associated with HIV worry and risk perception.

settingThis study is ongoing at 4 public health centers in Lilongwe, Malawi (2016-2017).

methodsAGYW of 15-24 years old were recruited to participate in a study assessing 4 models of service delivery. At each health center, participants completed a baseline survey assessing socioeconomic, behavioral, biomedical, and partnership characteristics; self-reported HIV status; and, if HIV-uninfected, HIV risk perception (high versus low or none) and HIV worry (any versus none). We analyzed associations between baseline characteristics and HIV prevalence, risk perception, and worry.

resultsAmong 1000 AGYW, median age was 19 years (IQR: 17-21). Thirty-three participants reported being HIV-infected. Fifteen characteristics were associated with HIV infection. Having more risk factors was associated with higher HIV prevalence (≤4 factors, 0.5%; 5-8 factors, 6%; >8 factors, 21%). Having more risk factors was also associated with higher risk perception (P < 0.001) and higher worry (P < 0.001). However, among those with ≥8 risk factors, 52% did not consider themselves to be at high risk and 21% did not report any HIV worry.

conclusionsMost AGYW perceive little risk of HIV acquisition, even those at highest risk. As a critical gap in the HIV prevention cascade, accurate risk perception is needed to tailor effective and sustained combination prevention strategies for this vulnerable population.

Indexed as

AdolescentCondomsFemaleHIV InfectionsHumansMalawiPerceptionPrevalenceRiskRisk FactorsSexual BehaviorSexually Transmitted DiseasesSexual PartnersSocioeconomic FactorsSurveys and QuestionnairesVulnerable Populations

Identifiers

PMID28991885
PMCPMC5720919
OpenAlexW2762666263

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.