Evidence map›Paper›PMID 28991881›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Scaling up Pediatric HIV Testing by Incorporating Provider-Initiated HIV Testing Into all Child Health Services in Hurungwe District, Zimbabwe.

Reuben Musarandega, Blessing Mutede, Agnes Mahomva, Wenceslas Nyamayaro, Angela Mushavi, Christina Lindan, Rhoderick Machekano

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Family Testing: An Index Case Finding Strategy to Close the Gaps in Pediatric HIV Diagnosis.Journal of acquired immune deficiency syndromes (1999) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Reuben MusarandegaElizabeth Glaser Pediatric AIDS Foundation, Harare, Zimbabwe.
Blessing MutedeElizabeth Glaser Pediatric AIDS Foundation, Harare, Zimbabwe.
Agnes MahomvaElizabeth Glaser Pediatric AIDS Foundation, Harare, Zimbabwe.
Wenceslas NyamayaroMinistry of Health and Child Care, Harare, Zimbabwe.
Angela MushaviMinistry of Health and Child Care, Harare, Zimbabwe.
Christina LindanGlobal Health Sciences, University of California, San Francisco, CA.
Rhoderick MachekanoElizabeth Glaser Pediatric AIDS Foundation, Washington, DC.

Funding

Int'l Traineeships in AIDS Prevention Studies (ITAPS)R25MH064712 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LINDAN, CHRISTINA P · 2002 to 2018
$3.4M
NIMH NIH HHS R25 MH064712
6 · The paper itself

Abstract

backgroundPractical ways are needed to scale-up pediatric HIV testing in sub-Saharan Africa, where testing is usually limited to HIV-exposed children in maternal and child health clinics.

methodsWe implemented an enhanced pediatric HIV testing program in 33 health facilities in Zimbabwe by integrating HIV testing into all pediatric health services. We collected individual data on children tested by having health care workers complete a program-specific child health booklet. We compared numbers of children tested before and during the program using routinely collected aggregate program data reported by health facilities.

resultsA total of 12,556 children aged 0-5 years were recorded in child health booklets; 9431 (75.1%) had information on HIV testing, of whom 7326 (77.7%) were tested; 7167 had test results of whom 122 (1.7%) were HIV-infected. Among children seen in outpatient clinics, 82.1% were tested compared with 66.5% tested among children seen in maternal/child health clinics. Of the 122 HIV-infected children identified, 77 (63.1%) could be missed under existing pediatric testing guidelines. The number of HIV-infected children identified during the 6-month program increased by 55% compared with the prior 6-month period (RR = 1.55, 95% CI: 1.22 to 1.96). Factors independently associated with HIV infection included being malnourished (adjusted odds ratio [AOR] = 7.7, 95% CI: 2.1 to 28.6), being exposed to TB (AOR = 8.1, 95% CI: 2.0 to 32.2), and having an HIV-infected mother (AOR = 41.6, 95% CI: 15.9 to 108.8).

conclusionsIntegrating HIV testing into all pediatric health services is feasible and can assist in identifying HIV-infected children who could be missed in current testing guidelines.

Indexed as

Child Health ServicesDelivery of Health Care, IntegratedHealth Plan ImplementationChild, PreschoolFemaleHealth FacilitiesHealth PersonnelHIV InfectionsHumansInfantInfant, NewbornMaleMass ScreeningZimbabwe

Identifiers

PMID28991881
PMCPMC5720897

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.