Evidence map›Paper›PMID 28991644›Full record

ReviewClinics in geriatric medicine2017

Inflammaging and the Lung.

Elizabeth J Kovacs, Devin M Boe, Lisbeth A Boule, Brenda J Curtis

Abstract readReview
In one paragraph

Review in Clinics in geriatric medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes: An Umbrella Review of Meta-analyses of Observational Studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Inflammation and aging: signaling pathways and intervention therapies.Signal transduction and targeted therapy · 2023
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Tuberculosis in an Aging World.Pathogens (Basel, Switzerland) · 2022
    Review
  17. Review
  18. Article
  19. Gender dimension in cardio-pulmonary continuum.Frontiers in cardiovascular medicine · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elizabeth J KovacsDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, Mucosal Inflammation Program, GILIIP (GI, Liver and Innate Immunity Program), Graduate Program in Immunology, IMAGE (Investigations in Metabolism, Aging, Gender and Exercise), University of Colorado Denver, Anschutz Medical Campus, 12700 East 19th Avenue, Research Complex 2, Mailstop #8620, Aurora, CO 80045, USA. Electronic address: elizabeth.kovacs@ucdenver.edu.
Devin M BoeDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, Mucosal Inflammation Program, Graduate Program in Immunology, University of Colorado Denver, Anschutz Medical Campus, 12700 East 19th Avenue, Research Complex 2, Room 6460, Aurora, CO 80045, USA.
Lisbeth A BouleDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, Mucosal Inflammation Program, IMAGE, University of Colorado Denver, Anschutz Medical Campus, 12700 East 19th Avenue, Research Complex 2, Room 6460, Aurora, CO 80045, USA.
Brenda J CurtisDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, Mucosal Inflammation Program, IMAGE, University of Colorado Denver, Anschutz Medical Campus, 12700 East 19th Avenue, Research Complex 2, Room 6018, Aurora, CO 80045, USA.

Funding

University of Colorado Aging Training GrantT32AG000279 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2001 to 2026
$10.1M
Aging, macrophage mediators, and burn trauma: SupplementR01AG018859 · NIA · UNIVERSITY OF COLORADO DENVER · PI KOVACS, ELIZABETH J. · 2001 to 2024
$7.6M
Ethanol Effects on Recovery after InjuryR01GM115257 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI KOVACS, ELIZABETH J. · 2015 to 2018
$1.7M
NIA NIH HHS R01 AG018859NIA NIH HHS T32 AG000279NIGMS NIH HHS R01 GM115257
6 · The paper itself

Abstract

With the coming of the "silver tsunami," expanding the knowledge about how various intrinsic and extrinsic factors affect the immune system in the elderly is timely and of immediate clinical need. The global population is increasing in age. By the year 2030, more than 20% of the population of the United States will be older than 65 years of age. This article focuses on how advanced age alters the immune systems and how this, in turn, modulates the ability of the aging lung to deal with infectious challenges from the outside world and from within the host.

Indexed as

Immune SystemImmunosenescenceAgedAgingHumansElderlyHost defenseImmunosenescenceInfectionInflammagingInflammationMacrophageNeutrophils

Identifiers

PMID28991644
PMCPMC5653264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.