Evidence map›Paper›PMID 28991549›Full record

ArticleChest2017

Vitamin C and Sepsis: Framing the Postpublication Discussion.

James M Walter, Benjamin D Singer

Abstract readLetterComment
In one paragraph

Article in Chest, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Any Role of High-Dose Vitamin C for Septic Shock in 2021?Seminars in respiratory and critical care medicine · 2021
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

James M WalterDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL. Electronic address: james.walter@northwestern.edu.
Benjamin D SingerDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.

Funding

Role of LUBAC and Na K-ATPase in Acute Lung InjuryP01HL071643 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CHANDEL, NAVDEEP S · 2003 to 2019
$30.8M
Training Program In Lung SciencesT32HL076139 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE, Jacob I Sznajder · 2004 to 2026
$9.6M
Regulatory T cell Uhrf1 and DNA methylation in repair of acute lung injuryK08HL128867 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SINGER, BENJAMIN DAVID · 2015 to 2019
$779k
NHLBI NIH HHS K08 HL128867NHLBI NIH HHS P01 HL071643NHLBI NIH HHS T32 HL076139
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

SepsisShock, SepticAscorbic AcidControlled Before-After StudiesHumansHydrocortisoneRetrospective StudiesThiamineAscorbic AcidHydrocortisoneThiamine

Identifiers

PMID28991549
PMCPMC6026228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.