Evidence map›Paper›PMID 28991505›Full record

ArticleChannels (Austin, Tex.)2018

Modulation of SK channels regulates locomotor alternating bursting activity in the functionally-mature spinal cord.

Amr A Mahrous, Sherif M Elbasiouny

Open access · goldAbstract read
In one paragraph

Article in Channels (Austin, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. A Multi-Scale, High-Fidelity Computational Model of the Mouse Triceps Surae Motor Pool.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025
    Article
  3. Article
  4. Article
  5. Contributions of h- and NaFrontiers in cellular neuroscience · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amr A Mahrousa Department of Neuroscience , Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University , Dayton , Ohio , USA.ORCID 0000-0001-9027-1960
Sherif M Elbasiounya Department of Neuroscience , Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University , Dayton , Ohio , USA.ORCID 0000-0002-6227-3894
Wright State University · US

Funding

The impact of neuromodulatory state on the excitability changes of motoneurons and the motor pool in ALSR01NS091836 · NINDS · WRIGHT STATE UNIVERSITY · PI Sherif M Elbasiouny · 2015 to 2026
$4.7M
NINDS NIH HHS R01 NS091836
6 · The paper itself

Abstract

The spinal cord contains specialized groups of cells called pattern generators, which are capable of orchestrating rhythmic firing activity in an isolated preparation. Different patterns of activity could be generated in vitro including right-left alternating bursting and bursting in which both sides are synchronized. The cellular and network mechanisms that enable these behaviors are not fully understood. We have recently shown that Ca

Indexed as

AnimalsFemaleLocomotionMaleMethoxamineMiceMice, Inbred StrainsPotassium Channels, Calcium-ActivatedSpinal CordMethoxaminePotassium Channels, Calcium-Activatedfictive locomotionmethoxamineneuronal burstingSK channelsspinal motoneurons

Identifiers

PMID28991505
PMCPMC5972800
OpenAlexW2762008042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.