Evidence map›Paper›PMID 28991397›Full record

ArticleInfluenza and other respiratory viruses2017

Record linkage study of the pathogen-specific burden of respiratory viruses in children.

Faye J Lim, Christopher C Blyth, Parveen Fathima, Nicholas de Klerk, Hannah C Moore

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Faye J LimWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, West Perth, WA, Australia.ORCID 0000-0002-6037-2741
Christopher C BlythWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, West Perth, WA, Australia.
Parveen FathimaWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, West Perth, WA, Australia.
Nicholas de KlerkWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, West Perth, WA, Australia.
Hannah C MooreWesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, The University of Western Australia, West Perth, WA, Australia.
The Kids Research Institute Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReliance on hospital discharge diagnosis codes alone will likely underestimate the burden of respiratory viruses.

objectivesTo describe the epidemiology of respiratory viruses more accurately, we used record linkage to examine data relating to all children hospitalized in Western Australia between 2000 and 2012. PATIENTS/

methodsWe extracted hospital, infectious disease notification and laboratory data of a cohort of children born in Western Australia between 1996 and 2012. Laboratory records of respiratory specimens collected within 48 hours of admission were linked to hospitalization records. We calculated the frequency and rates of virus detection. To identify groups where under-ascertainment for respiratory viruses was greatest, we used logistic regression to determine factors associated with failure to test. RESULTS AND

conclusionsNine percentage of 484 992 admissions linked to a laboratory record for respiratory virus testing. While 62% (n = 26 893) of laboratory-confirmed admissions received respiratory infection diagnosis codes, 38% (n = 16 734) had other diagnoses, notably viral infection of unspecified sites. Of those tested, incidence rates were highest for respiratory syncytial virus (247 per 100 000 child-years) followed by parainfluenza (63 per 100 000 child-years). Admissions among older children and those without a respiratory diagnosis were associated with failure to test for respiratory viruses. Linked data can significantly enhance diagnostic codes when estimating the true burden of disease. In contrast to current emphasis on influenza, respiratory syncytial virus and parainfluenza were the most common viral pathogens among hospitalized children. By characterizing those failing to be tested, we can begin to quantify the under-ascertainment of respiratory viruses.

Indexed as

AdolescentChildChild, HospitalizedChild, PreschoolClinical Laboratory TechniquesCohort StudiesCost of IllnessFemaleHospitalizationHumansInfantInfant, NewbornInfluenza, HumanMaleMedical RecordsParamyxoviridae Infectionsepidemiologyhospitalizationhuman parainfluenza virushuman respiratory syncytial virusmedical record linkage

Identifiers

PMID28991397
PMCPMC5705691
OpenAlexW2762775524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.