Evidence map›Paper›PMID 28991254›Full record

ArticleNature genetics2017

The draft genome of tropical fruit durian (Durio zibethinus).

Bin Tean Teh, Kevin Lim, Chern Han Yong, Cedric Chuan Young Ng, Sushma Ramesh Rao, Vikneswari Rajasegaran, Weng Khong Lim, Choon Kiat Ong, Ki Chan, Vincent Kin Yuen Cheng and 5 more

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Article in Nature genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
39.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 261 citations in OpenAlex.

  1. Article
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  9. Review
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  11. The genomic design of fruit metabolomes.Plant communications · 2025
    Review
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  14. Review
  15. Article
  16. Article
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Bin Tean TehThorn Biosystems Pte Ltd, Singapore.ORCID http://orcid.org/0000-0003-1514-1124
Kevin LimProgram in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore.ORCID http://orcid.org/0000-0002-3822-1242
Chern Han YongProgram in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore.
Cedric Chuan Young NgLaboratory of Cancer Epigenome, Division of Medical Science, National Cancer Centre singapore, Singapore.
Sushma Ramesh RaoDepartment of Biological Sciences, National University of Singapore, Singapore.
Vikneswari RajasegaranLaboratory of Cancer Epigenome, Division of Medical Science, National Cancer Centre singapore, Singapore.
Weng Khong LimProgram in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore.ORCID http://orcid.org/0000-0003-4391-1130
Choon Kiat OngMetabolites Biology Laboratory, National University of Singapore, Singapore.ORCID http://orcid.org/0000-0001-6402-4288
Ki ChanGlobal Databank, Singapore.
Vincent Kin Yuen ChengVerdant Foundation, Hong Kong.
Poh Sheng SohSamsoney Group, Johor Bahru, Malaysia.
Sanjay SwarupDepartment of Biological Sciences, National University of Singapore, Singapore.
Steven G RozenProgram in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore.ORCID http://orcid.org/0000-0002-4288-0056
Niranjan NagarajanGenome Institute of Singapore, Singapore.
Patrick TanThorn Biosystems Pte Ltd, Singapore.
SingHealth · SGNational University of Singapore · SGDuke-NUS Medical School · SGNational Cancer Centre Singapore · SGGenome Institute of Singapore · SGGlobalFoundries (Singapore) · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Durian (Durio zibethinus) is a Southeast Asian tropical plant known for its hefty, spine-covered fruit and sulfury and onion-like odor. Here we present a draft genome assembly of D. zibethinus, representing the third plant genus in the Malvales order and first in the Helicteroideae subfamily to be sequenced. Single-molecule sequencing and chromosome contact maps enabled assembly of the highly heterozygous durian genome at chromosome-scale resolution. Transcriptomic analysis showed upregulation of sulfur-, ethylene-, and lipid-related pathways in durian fruits. We observed paleopolyploidization events shared by durian and cotton and durian-specific gene expansions in MGL (methionine γ-lyase), associated with production of volatile sulfur compounds (VSCs). MGL and the ethylene-related gene ACS (aminocyclopropane-1-carboxylic acid synthase) were upregulated in fruits concomitantly with their downstream metabolites (VSCs and ethylene), suggesting a potential association between ethylene biosynthesis and methionine regeneration via the Yang cycle. The durian genome provides a resource for tropical fruit biology and agronomy.

Indexed as

Genome, PlantTranscriptomeAmino Acids, CyclicBombacaceaeCarbon-Sulfur LyasesChromosome MappingFruitHigh-Throughput Nucleotide SequencingLigasesLipid MetabolismPhylogenyPlant ProteinsSulfurVolatile Organic Compounds1-aminocyclopropane-1-carboxylic acidAmino Acids, CyclicCarbon-Sulfur LyasesLigasesL-methionine gamma-lyasePlant ProteinsSulfurVolatile Organic Compounds

Identifiers

PMID28991254
OpenAlexW2764305907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.