Evidence map›Paper›PMID 28991228›Full record

ArticleOncogene2018

Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma.

S Lee, P Liu, R Teinturier, J Jakob, M Tschaffon, A Tasdogan, R Wittig, S Hoeller, D Baumhoer, L Frappart and 4 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Oncogene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Molecular findings in maxillofacial bone tumours and its diagnostic value.Virchows Archiv : an international journal of pathology · 2020
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 3 countries.

S LeeInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.
P LiuInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.
R TeinturierCentre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR5286, Université Lyon 1, Lyon, France.
J JakobLeibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.
M TschaffonInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.
A TasdoganInstitute for Immunology, University Hospital Ulm, Ulm, Germany.
R WittigInstitute for Laser Technologies in Medicine and Metrology at Ulm University, Ulm, Germany.
S HoellerBone Tumour Reference Centre and DOESAK Registry, Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland.
D BaumhoerBone Tumour Reference Centre and DOESAK Registry, Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland.
L FrappartLeibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.
S VettorazziInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.
P BertolinoCentre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR5286, Université Lyon 1, Lyon, France.
C ZhangCentre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR5286, Université Lyon 1, Lyon, France.
J TuckermannInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.
Universität Ulm · DELeibniz Institute on Aging - Fritz Lipmann Institute (FLI) · DEUniversity Hospital of Basel · CHCentre de Recherche en Cancérologie de Lyon · FRCentre National de la Recherche Scientifique · FRInstitute for Laser Technology in Medicine and Measurement Technique · DEUniversité Claude Bernard Lyon 1 · FRUniversity Hospital Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ossifying fibroma (OF) is a rare benign tumor of the craniofacial bones that can reach considerable and disfiguring dimensions if left untreated. Although the clinicopathological characteristics of OF are well established, the underlying etiology has remained largely unknown. Our work indicates that Men1-a tumor suppressor gene responsible of Multiple endocrine neoplasia type 1-is critical for OF formation and shows that mice with targeted disruption of Men1 in osteoblasts (Men1

Indexed as

AnimalsCell DifferentiationCell ProliferationCyclin-Dependent Kinase Inhibitor p21Disease Models, AnimalDown-RegulationFibroma, OssifyingHumansMaleMandibleMiceMice, TransgenicMultiple Endocrine Neoplasia Type 1OsteoblastsOsteogenesisPrimary Cell CultureCdkn1a protein, mouseCyclin-Dependent Kinase Inhibitor p21Men1 protein, mouseProto-Oncogene Proteins

Identifiers

PMID28991228
OpenAlexW2763420936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.