Evidence map›Paper›PMID 28991212›Full record

ArticleInternational journal of molecular sciences2017

Evaluating the Effects of an Organic Extract from the Mediterranean Sponge Geodia cydonium on Human Breast Cancer Cell Lines.

Susan Costantini, Eliana Guerriero, Roberta Teta, Francesca Capone, Alessia Caso, Angela Sorice, Giovanna Romano, Adrianna Ianora, Nadia Ruocco, Alfredo Budillon and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Anticonvulsant Activity ofMolecules (Basel, Switzerland) · 2022
    Article
  3. Review
  4. Organic extract ofOncology letters · 2022
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Effects of α-zearalenol on the metabolome of two breast cancer cell lines by 1H-NMR approach.Metabolomics : Official journal of the Metabolomic Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Susan CostantiniExperimental Pharmacology Unit, Istituto Nazionale Tumori "Fondazione G. Pascale"-IRCCS, 80131 Napoli, Italy. s.costantini@istitutotumori.na.it.
Eliana GuerrieroExperimental Pharmacology Unit, Istituto Nazionale Tumori "Fondazione G. Pascale"-IRCCS, 80131 Napoli, Italy. e.guerriero@istitutotumori.na.it.
Roberta TetaDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy. roberta.teta@unina.it.
Francesca CaponeExperimental Pharmacology Unit, Istituto Nazionale Tumori "Fondazione G. Pascale"-IRCCS, 80131 Napoli, Italy. f.capone@istitutotumori.na.it.
Alessia CasoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy. alessia.caso@unina.it.
Angela SoriceExperimental Pharmacology Unit, Istituto Nazionale Tumori "Fondazione G. Pascale"-IRCCS, 80131 Napoli, Italy. a.sorice@istitutotumori.na.it.
Giovanna RomanoDepartment of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. romano@szn.it.
Adrianna IanoraDepartment of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. ianora@szn.it.
Nadia RuoccoDepartment of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. nadia.ruocco@szn.it.
Alfredo BudillonExperimental Pharmacology Unit, Istituto Nazionale Tumori "Fondazione G. Pascale"-IRCCS, 80131 Napoli, Italy. a.budillon@istitutotumori.na.it.
Valeria CostantinoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy. costanti@unina.it.ORCID 0000-0001-8723-9505
Maria CostantiniDepartment of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. maria.costantini@szn.it.
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITStazione Zoologica Anton Dohrn · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine sponges are an excellent source of bioactive secondary metabolites for pharmacological applications. In the present study, we evaluated the chemistry, cytotoxicity and metabolomics of an organic extract from the Mediterranean marine sponge

Indexed as

AnimalsApoptosisBreast NeoplasmsCell Line, TumorCell ProliferationGeodiaGlycolysisGlycosphingolipidsHumansMCF-7 CellsPlant ExtractsGlycosphingolipidsPlant Extractsbreast cancercytokinescytotoxicitymetabolomicssponges

Identifiers

PMID28991212
PMCPMC5666794
OpenAlexW2763691545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.