Evidence map›Paper›PMID 28991176›Full record

ReviewViruses2017

Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins.

Shun Chen, Zhen Wu, Mingshu Wang, Anchun Cheng

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
  2. Article
  3. Lipid Architecture in the Zika Virus.ACS physical chemistry Au · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Comparative analysis of duck Tembusu virus Cluster 1 and Cluster 2.1 inCurrent research in parasitology & vector-borne diseases · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Extracellular Vesicles inInternational journal of molecular sciences · 2024
    Review
  18. Review
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shun ChenInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. shunchen@sicau.edu.cn.
Zhen WuInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. zhenwu@stu.sicau.edu.cn.
Mingshu WangInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. mshwang@163.com.
Anchun ChengInstitute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. chenganchun@vip.163.com.ORCID 0000-0001-6093-353X
Sichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flaviviridae-caused diseases are a critical, emerging public health problem worldwide. Flaviviridae infections usually cause severe, acute or chronic diseases, such as liver damage and liver cancer resulting from a hepatitis C virus (HCV) infection and high fever and shock caused by yellow fever. Many researchers worldwide are investigating the mechanisms by which Flaviviridae cause severe diseases. Flaviviridae can interfere with the host's innate immunity to achieve their purpose of proliferation. For instance, dengue virus (DENV) NS2A, NS2B3, NS4A, NS4B and NS5; HCV NS2, NS3, NS3/4A, NS4B and NS5A; and West Nile virus (WNV) NS1 and NS4B proteins are involved in immune evasion. This review discusses the interplay between viral non-structural Flaviviridae proteins and relevant host proteins, which leads to the suppression of the host's innate antiviral immunity.

Indexed as

Immune EvasionImmunity, InnateAnimalsAntiviral AgentsFlaviviridaeFlaviviridae InfectionsHumansMiceViral Nonstructural ProteinsAntiviral AgentsViral Nonstructural ProteinsemergenceflavivirusHCVimmune evasionnon-structural protein

Identifiers

PMID28991176
PMCPMC5691642
OpenAlexW2763801778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.