Evidence map›Paper›PMID 28991126›Full record

ArticleJournal of pediatric hematology/oncology2018

Successful Treatment of Invasive Conidiobolus Infection During Therapy for Acute Lymphoblastic Leukemia.

Craig Erker, Anna R Huppler, Thomas J Walsh, Michael E McCormick, Mariko Suchi, Neel S Bhatt, Susan C Kehl, Jessica Southwood, Paul Harker-Murray

Abstract readCase Reports
In one paragraph

Article in Journal of pediatric hematology/oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. InvasiveASM case reports · 2026
    Article
  2. Article
  3. Article
  4. Conidiobolomycosis, cryptococcosis, and aspergillosis in sheep and goats: a review.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Craig ErkerDepartments of Pediatrics.
Anna R HupplerDepartments of Pediatrics.
Thomas J WalshTransplantation-Oncology Infectious Diseases Program, Weill Cornell Medical Center of Cornell University, New York City, NY.
Michael E McCormickOtolaryngology.
Mariko SuchiPathology, Medical College of Wisconsin, Milwaukee, WI.
Neel S BhattDepartments of Pediatrics.
Susan C KehlPathology, Medical College of Wisconsin, Milwaukee, WI.
Jessica SouthwoodOtolaryngology.
Paul Harker-MurrayDepartments of Pediatrics.

Funding

Anti-Candida activity of CCL28 in oropharyngeal candidiasisK08DE026189 · NIDCR · MEDICAL COLLEGE OF WISCONSIN · PI HUPPLER, ANNA · 2017 to 2021
$860k
NIDCR NIH HHS K08 DE026189
6 · The paper itself

Abstract

Invasive fungal infections are a serious cause of morbidity and mortality in patients with hematologic malignancies. Conidiobolus species are molds within the order Entomophthorales and may disseminate to become rapidly fatal in immunocompromised individuals. This species of fungal infections are often multidrug resistant (MDR) and present unique therapeutic challenges. Reports of Conidiobolus infections are rare in pediatric oncology. We report the successful treatment of an adolescent male with B-cell lymphoblastic leukemia and MDR invasive sinopulmonary Conidiobolus infection with emphasis on early and aggressive neutrophil support with surgical debridement. The strategies described could be applied to other MDR fungal infections.

Indexed as

AdolescentAntifungal AgentsConidiobolusDrug Resistance, MultipleGranulocyte-Macrophage Colony-Stimulating FactorGranulocytesHumansMaleMycosesPrecursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaRemission InductionZygomycosisAntifungal AgentsGranulocyte-Macrophage Colony-Stimulating Factor

Identifiers

PMID28991126
PMCPMC5904005

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.