ArticleEpidemiology (Cambridge, Mass.)2018
Site-specific Solid Cancer Mortality After Exposure to Ionizing Radiation: A Cohort Study of Workers (INWORKS).
Article in Epidemiology (Cambridge, Mass.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Deep Breaths: A Systematic Review of the Potential Effects of Employment in the Nuclear Industry on Mortality from Non-Malignant Respiratory Disease.Radiation research · 2022Pooled it
- Ionizing radiation exposure during adulthood and risk of developing central nervous system tumors: systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Radiation Exposure and Cancer Mortality in Populations Living Around the Semipalatinsk Nuclear Test Site in Kazakhstan.International journal of environmental research and public health · 2026Article
- Sex-specific radiation-associated lung cancer mortality risks as impacted by smoking among US radiological technologists.Journal of the National Cancer Institute · 2025Article
- Site-specific cancer mortality after low-level exposure to ionizing radiation: findings from an update of the International Nuclear Workers Study (INWORKS).American journal of epidemiology · 2025Article
- Updated findings on temporal variation in radiation-effects on cancer mortality in an international cohort of nuclear workers (INWORKS).European journal of epidemiology · 2024Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Incidence risk of hepatobiliary malignant neoplasms in the cohort of workers chronically exposed to ionizing radiation.Scientific reports · 2024Article
- Radiation-Related Thyroid Cancer.Endocrine reviews · 2024Review
- Third mortality follow-up of the Mallinckrodt uranium processing workers, 1942-2019.International journal of radiation biology · 2024Article
- Cancer mortality after low dose exposure to ionising radiation in workers in France, the United Kingdom, and the United States (INWORKS): cohort study.BMJ (Clinical research ed.) · 2023Article
- Ionizing radiation and solid cancer mortality among US nuclear facility workers.International journal of epidemiology · 2023Article
- How Does Environmental and Occupational Exposure Contribute to Carcinogenesis in Genitourinary and Lung Cancers?Cancers · 2023Review
- Comparison of Proportional Mortality Between Korean Atomic Bomb Survivors and the General Population During 1992-2019.Journal of Korean medical science · 2023Article
- Updated Mortality Analysis of SELTINE, the French Cohort of Nuclear Workers, 1968-2014.Cancers · 2022Article
- Low-Dose Extrapolation Factors Implied by Mortality and Incidence Data from the Japanese Atomic Bomb Survivor Life Span Study Data.Radiation research · 2022Article
- Metal nanoparticles as a promising technology in targeted cancer treatment.Drug delivery · 2022Review
- Risk of thyroid cancer in Ukrainian cleanup workers following the Chornobyl accident.European journal of epidemiology · 2022Article
- Sex-specific lung cancer risk among radiation workers in the million-person study and patients TB-Fluoroscopy.International journal of radiation biology · 2022Article
- Transcriptomic analysis links hepatocellular carcinoma (HCC) in HZE ion irradiated mice to a human HCC subtype with favorable outcomes.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundThere is considerable scientific interest in associations between protracted low-dose exposure to ionizing radiation and the occurrence of specific types of cancer.
methodsAssociations between ionizing radiation and site-specific solid cancer mortality were examined among 308,297 nuclear workers employed in France, the United Kingdom, and the United States. Workers were monitored for external radiation exposure and follow-up encompassed 8.2 million person-years. Radiation-mortality associations were estimated using a maximum-likelihood method and using a Markov chain Monte Carlo method, the latter used to fit a hierarchical regression model to stabilize estimates of association.
resultsThe analysis included 17,957 deaths attributable to solid cancer, the most common being lung, prostate, and colon cancer. Using a maximum-likelihood method to quantify associations between radiation dose- and site-specific cancer, we obtained positive point estimates for oral, esophagus, stomach, colon, rectum, pancreas, peritoneum, larynx, lung, pleura, bone and connective tissue, skin, ovary, testis, and thyroid cancer; in addition, we obtained negative point estimates for cancer of the liver and gallbladder, prostate, bladder, kidney, and brain. Most of these estimated coefficients exhibited substantial imprecision. Employing a hierarchical model for stabilization had little impact on the estimated associations for the most commonly observed outcomes, but for less frequent cancer types, the stabilized estimates tended to take less extreme values and have greater precision than estimates obtained without such stabilization.
conclusionsThe results provide further evidence regarding associations between low-dose radiation exposure and cancer.
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