Evidence map›Paper›PMID 28990920›Full record

ArticleThe American journal of tropical medicine and hygiene2017

Malaria Control Interventions Contributed to Declines in Malaria Parasitemia, Severe Anemia, and All-Cause Mortality in Children Less Than 5 Years of Age in Malawi, 2000-2010.

Christine L Hershey, Lia S Florey, Doreen Ali, Adam Bennett, Misheck Luhanga, Don P Mathanga, S René Salgado, Carrie F Nielsen, Peter Troell, Gomezgani Jenda and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
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  6. Approaches to Address the Anemia Challenge.The Journal of nutrition · 2023
    Article
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  9. Observational
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  18. Asymptomatic SubmicroscopicThe American journal of tropical medicine and hygiene · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Christine L HersheyPresident's Malaria Initiative, Agency for International Development, Washington, District of Columbia.
Lia S FloreyThe DHS Program, ICF International, Rockville, Maryland.
Doreen AliNational Malaria Control Program, Lilongwe, Malawi.
Adam BennettGlobal Health Group, University of California San Francisco School of Medicine, San Francisco, California.
Misheck LuhangaNational Malaria Control Program, Lilongwe, Malawi.
Don P MathangaMalaria Alert Centre, College of Medicine, Blantyre, Malawi.
S René SalgadoPresident's Malaria Initiative, Agency for International Development, Washington, District of Columbia.
Carrie F NielsenPresident's Malaria Initiative, Malaria Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Peter TroellPresident's Malaria Initiative, Centers for Disease Control and Prevention, Lilongwe, Malawi.
Gomezgani JendaPresident's Malaria Initiative, Agency for International Development, Lilongwe, Malawi.
Yazoume YéMEASURE Evaluation, ICF International, Rockville, Maryland.
Achuyt BhattaraiPresident's Malaria Initiative, Malaria Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Centers for Disease Control and Prevention · USICF International (United States) · USPublic Health Institute of Malawi · MWU.S. President's Malaria Initiative · USAfrican Institute for Development Policy · MWUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria control intervention coverage increased nationwide in Malawi during 2000-2010. Trends in intervention coverage were assessed against trends in malaria parasite prevalence, severe anemia (hemoglobin < 8 g/dL), and all-cause mortality in children under 5 years of age (ACCM) using nationally representative household surveys. Associations between insecticide-treated net (ITN) ownership, malaria morbidity, and ACCM were also assessed. Household ITN ownership increased from 27.4% (95% confidence interval [CI] = 25.9-29.0) in 2004 to 56.8% (95% CI = 55.6-58.1) in 2010. Similarly intermittent preventive treatment during pregnancy coverage increased from 28.2% (95% CI = 26.7-29.8) in 2000 to 55.0% (95% CI = 53.4-56.6) in 2010. Malaria parasite prevalence decreased significantly from 60.5% (95% CI = 53.0-68.0) in 2001 to 20.4% (95% CI = 15.7-25.1) in 2009 in children aged 6-35 months. Severe anemia prevalence decreased from 20.4% (95% CI: 17.3-24.0) in 2004 to 13.1% (95% CI = 11.0-15.4) in 2010 in children aged 6-23 months. ACCM decreased 41%, from 188.6 deaths per 1,000 live births (95% CI = 179.1-198.0) during 1996-2000, to 112.1 deaths per 1,000 live births (95% CI = 105.8-118.5) during 2006-2010. When controlling for other covariates in random effects logistic regression models, household ITN ownership was protective against malaria parasitemia in children (odds ratio [OR] = 0.81, 95% CI = 0.72-0.92) and severe anemia (OR = 0.82, 95% CI = 0.72-0.94). After considering the magnitude of changes in malaria intervention coverage and nonmalaria factors, and given the contribution of malaria to all-cause mortality in malaria-endemic countries, the substantial increase in malaria control interventions likely improved child survival in Malawi during 2000-2010.

Indexed as

AnemiaAntimalarialsChild MortalityChild, PreschoolCommunicable Disease ControlHumansInfantInfant MortalityInsecticide-Treated BednetsMalariaMalawiMosquito ControlNational Health ProgramsOdds RatioParasitemiaRetrospective StudiesAntimalarials

Identifiers

PMID28990920
PMCPMC5619935
OpenAlexW2759735128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.