Evidence map›Paper›PMID 28990866›Full record

ArticleSocial neuroscience2018

Neuroanatomical correlates of emotion-processing in children with unilateral brain lesion: A preliminary study of limbic system organization.

Rowena Ng, Philip Lai, Timothy T Brown, Anna Järvinen, Eric Halgren, Ursula Bellugi, Doris Trauner

Abstract read
In one paragraph

Article in Social neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rowena Nga Laboratory for Cognitive Neuroscience , Salk Institute for Biological Studies , La Jolla , CA , USA.
Philip Laic San Diego State University/University of California, San Diego Joint Doctoral Program in Language and Communicative Disorders , San Diego , CA , USA.
Timothy T Brownd Center for Multimodal Imaging and Genomics , University of California San Diego , La Jolla , CA , USA.
Anna Järvinena Laboratory for Cognitive Neuroscience , Salk Institute for Biological Studies , La Jolla , CA , USA.
Eric Halgrend Center for Multimodal Imaging and Genomics , University of California San Diego , La Jolla , CA , USA.
Ursula Bellugia Laboratory for Cognitive Neuroscience , Salk Institute for Biological Studies , La Jolla , CA , USA.
Doris Traunerf Department of Neurosciences , University of California, San Diego School of Medicine , La Jolla , CA , USA.

Funding

Williams Syndrome: The Molecular Genetic CharacterizationP01HD033113 · NICHD · UNIVERSITY OF UTAH · PI HALGREN, ERIC · 1996 to 2015
$19.4M
VARIANTS OF FOCAL BRAIN INJURYP50NS022343 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CEPONIENE, RITA · 1985 to 2012
$15.1M
TRAINING PROGRAM IN COGNITIVE NEUROSCIENCET32MH020002 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SEJNOWSKI, TERRENCE J · 1999 to 2020
$6.1M
Neurocognitive Approaches to Communication DisordersT32DC007361 · NIDCD · SAN DIEGO STATE UNIVERSITY · PI Tracy Love-Geffen · 2005 to 2026
$3.9M
NICHD NIH HHS P01 HD033113NIDCD NIH HHS T32 DC007361NIMH NIH HHS T32 MH020002NINDS NIH HHS P50 NS022343
6 · The paper itself

Abstract

In this study, MRI and DTI were employed to examine subcortical volume and microstructural properties (FA, MD) of the limbic network, and their relationships with affect discrimination in 13 FL (6 right FL, M = 10.17 years; 7 left FL; M = 10.09) and 13 typically-developing children (TD; M = 10.16). Subcortical volume of the amygdala, hippocampus and thalamus and FA and MD of the fornix and anterior thalamic radiation (ATR) were examined. Results revealed no group differences across emotion-perception tasks or amygdalar volume. However, contrasting neuroanatomical patterns were observed in right versus left FL youth. Right FL participants showed increased left hippocampal and thalamic volume relative to left FL participants; whereas, the latter group showed increased right thalamic volume. DTI findings also indicated right FL children show greater MD of right fornix than other groups, whereas, left FL youth showed greater MD of left fornix. Right FL youth also showed lower FA of right fornix than left FL children, whereby the latter showed greater FA of left fornix and ATR. Differential associations between DTI indices and auditory/visual emotion-perception were observed across FL groups. Findings indicate diverging brain-behavioral relationships for emotion-perception among right and left FL children.

Indexed as

Acoustic StimulationAdolescentBrainChildDiffusion Tensor ImagingEmotionsFemaleFunctional LateralityHumansLimbic SystemMagnetic Resonance ImagingMalePhotic Stimulationanterior thalamic radiationDTIemotion perceptionFocal lesionfornixlimbic system

Identifiers

PMID28990866
PMCPMC6117211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.