Evidence map›Paper›PMID 28990846›Full record

ArticlePlant signaling & behavior2017

Aldehyde dehydrogenases may modulate signaling by lipid peroxidation-derived bioactive aldehydes.

Missihoun D Tagnon, Kotchoni O Simeon

Open access · bronzeAbstract read
In one paragraph

Article in Plant signaling & behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 34 citations in OpenAlex.

  1. The Aldehyde Dehydrogenase Superfamily inInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Missihoun D Tagnona Department of Biology , Rutgers University , Camden , NJ , USA.
Kotchoni O Simeona Department of Biology , Rutgers University , Camden , NJ , USA.
Rutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aldehyde molecules were shown to induce gene expression but because of their toxicity, the cell expresses ALDEHYDE DEHYDROGENASES (ALDH, EC 1.2.1.3) that oxidize them to carboxylic acids. To understand how the aldehydes may be both toxic and gene activators, we expressed the ALDH7B4 gene promoter fused to the β-glucuronidase reporter gene in independent transgenic lines and found that pentanal and trans-2-hexenal activated the promoter whereas trans-2-hexenal induced the ALDH7B4 protein. Paraquat led to higher amounts of malondialdehyde compared to trans-2-hexenal and H

Indexed as

Aldehyde DehydrogenaseAldehydesArabidopsis ProteinsHydrogen PeroxideLipid PeroxidationMalondialdehydeOxidation-ReductionPromoter Regions, GeneticSignal Transduction2-hexenalAldehyde DehydrogenaseAldehydesALDH7B4 protein, ArabidopsisArabidopsis ProteinsHydrogen PeroxideMalondialdehydeAldehyde Dehydrogenasecarbonylationlipid peroxidationreactive carbonyl speciessignallingα,β-unsaturated aldehydes

Identifiers

PMID28990846
PMCPMC5703241
OpenAlexW2763437068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.