Evidence map›Paper›PMID 28990374›Full record

ArticleJournal of Zhejiang University. Science. B

Transcriptome sequencing and annotation of the halophytic microalga Dunaliella salina.

Ling Hong, Jun-Li Liu, Samira Z Midoun, Philip C Miller

Abstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ling HongDepartment of Genetics and Developmental Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Jun-Li LiuDepartment of Genetics and Developmental Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Samira Z MidounDepartment of Genetics and Developmental Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Philip C MillerSystems Biology Research Group, Bioengineering Department, University of California, 9500 Gilman Dr. San Diego, La Jolla, CA 92093, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unicellular green alga Dunaliella salina is well adapted to salt stress and contains compounds (including β-carotene and vitamins) with potential commercial value. A large transcriptome database of D. salina during the adjustment, exponential and stationary growth phases was generated using a high throughput sequencing platform. We characterized the metabolic processes in D. salina with a focus on valuable metabolites, with the aim of manipulating D. salina to achieve greater economic value in large-scale production through a bioengineering strategy. Gene expression profiles under salt stress verified using quantitative polymerase chain reaction (qPCR) implied that salt can regulate the expression of key genes. This study generated a substantial fraction of D. salina transcriptional sequences for the entire growth cycle, providing a basis for the discovery of novel genes. This first full-scale transcriptome study of D. salina establishes a foundation for further comparative genomic studies.

Indexed as

TranscriptomeCarotenoidsMicroalgaeSalt-Tolerant PlantsCarotenoidsDunaliella salina; Transcriptome profile; Metabolic processes and adjustment; Regulatory metabolism; Salt stress

Identifiers

PMID28990374
PMCPMC5633768

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.