Evidence map›Paper›PMID 28990332›Full record

ArticleJournal of cellular and molecular medicine2018

The expression and functional activities of smooth muscle myosin and non-muscle myosin isoforms in rat prostate.

Ping Chen, Jing Yin, Yu-Ming Guo, He Xiao, Xing-Huan Wang, Michael E DiSanto, Xin-Hua Zhang

Abstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  9. Article
  10. Filament evanescence of myosin II and smooth muscle function.The Journal of general physiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ping ChenDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Jing YinDepartment of Rehabilitation, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yu-Ming GuoDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
He XiaoDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xing-Huan WangDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Michael E DiSantoDepartment of Surgery and Biomedical Sciences of Cooper Medical School of Rowan University, Camden, NJ, USA.
Xin-Hua ZhangDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.ORCID 0000-0003-0267-428X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benign prostatic hyperplasia (BPH) is mainly caused by increased prostatic smooth muscle (SM) tone and volume. SM myosin (SMM) and non-muscle myosin (NMM) play important roles in mediating SM tone and cell proliferation, but these molecules have been less studied in the prostate. Rat prostate and cultured primary human prostate SM and epithelial cells were utilized. In vitro organ bath studies were performed to explore contractility of rat prostate. SMM isoforms, including SM myosin heavy chain (MHC) isoforms (SM1/2 and SM-A/B) and myosin light chain 17 isoforms (LC

Indexed as

Amino Acid SequenceAnimalsCarbacholEpithelial CellsMaleMuscle ContractionMyocytes, Smooth MuscleMyosin Type IINitroprussideOrgan SpecificityPhenylephrinePotassium ChlorideProstateProtein IsoformsRats, Sprague-DawleySmooth Muscle MyosinsCarbacholMyosin Type IINitroprussidePhenylephrinePotassium ChlorideProtein IsoformsSmooth Muscle Myosinsisoformsmyosinnon-muscle myosinprostatesmooth muscle

Identifiers

PMID28990332
PMCPMC5742693

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.