Evidence map›Paper›PMID 28990185›Full record

ReviewAnnals of the New York Academy of Sciences2017

Postaxial limb hypoplasia (PALH): the classification, clinical features, and related developmental biology.

Zeng Zhang, Dan Yi, Rong Xie, John L Hamilton, Qing-Lin Kang, Di Chen

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Annals of the New York Academy of Sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zeng ZhangDepartment of Orthopedic Surgery, Shanghai Jiao-Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Dan YiDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
Rong XieDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
John L HamiltonDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
Qing-Lin KangDepartment of Orthopedic Surgery, Shanghai Jiao-Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Di ChenDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
Rush University Medical Center · USShanghai Jiao Tong University · CN

Funding

The Mechanism through which TGF-Beta Maintains Chondrocytes in Proliferating StagR01AR054465 · NIAMS · UNIVERSITY OF ROCHESTER · PI CHEN, DI · 2007 to 2018
$2.7M
The Role of MicroRNA in Osteoarthritis: Alzheimer's Administrative SupplementR01AR070222 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI HUANG, JIAN, ZHAO, LAN · 2017 to 2022
$2.1M
Pain Mechanisms of Knee Joint OsteoarthritisR01AR062136 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI CHEN, DI · 2012 to 2016
$1.7M
Allosteric Small Molecule Inhibitor Of Nerve Growth Factor Signaling in Low Back PainR21AR067935 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI CHEN, DI · 2015 to 2016
$375k
Anti-VEGF Therapy in Osteoarthritis and Associated PainF31AR070002 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI HAMILTON, JOHN L · 2016 to 2017
$84k
NIAMS NIH HHS F31 AR070002NIAMS NIH HHS R01 AR054465NIAMS NIH HHS R01 AR062136NIAMS NIH HHS R01 AR070222NIAMS NIH HHS R21 AR067935
6 · The paper itself

Abstract

Postaxial limb hypoplasia (PALH) is a group of nonhereditary diseases with congenital lower limb deficiency affecting the fibular ray, including fibular hemimelia, proximal femoral focal deficiency, and tarsal coalition. The etiology and the developmental biology of the anomaly are still not fully understood. Here, we review the previous classification systems, present the clinical features, and discuss the developmental biology of PALH.

Indexed as

MutationEctromeliaFibulaGenetic Predisposition to DiseaseHumansLimb Deformities, CongenitalMusculoskeletal DevelopmentSignal Transductionfibular hemimeliapostaxial hypoplasiaproximal femoral focal deficiencyskeletal developmenttarsal coalitionWnt signaling

Identifiers

PMID28990185
PMCPMC5730483
OpenAlexW2763988733

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.