Evidence map›Paper›PMID 28989980›Full record

ArticleWellcome open research2017

Bone mineral density and risk of type 2 diabetes and coronary heart disease: A Mendelian randomization study.

Wei Gan, Robert J Clarke, Anubha Mahajan, Benard Kulohoma, Hidetoshi Kitajima, Neil R Robertson, N William Rayner, Robin G Walters, Michael V Holmes, Zhengming Chen and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Wellcome open research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Large-Scale Phenome-Wide Association Study ofCirculation. Genomic and precision medicine · 2018
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Wei GanWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.ORCID https://orcid.org/0000-0002-1270-6495
Robert J ClarkeBig Data Institute, University of Oxford, Oxford, OX3 7FZ, UK.
Anubha MahajanWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Benard KulohomaWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.ORCID https://orcid.org/0000-0001-6825-1832
Hidetoshi KitajimaWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Neil R RobertsonWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
N William RaynerWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Robin G WaltersBig Data Institute, University of Oxford, Oxford, OX3 7FZ, UK.ORCID https://orcid.org/0000-0002-9179-0321
Michael V HolmesBig Data Institute, University of Oxford, Oxford, OX3 7FZ, UK.ORCID https://orcid.org/0000-0001-6617-0879
Zhengming ChenBig Data Institute, University of Oxford, Oxford, OX3 7FZ, UK.
Mark I McCarthyWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
University of Copenhagen · DKOpen Data Institute · GBCentre for Human Genetics · GBUniversity of Nairobi · KE

Funding

Identifying variants causal for Type 2 Diabetes in Major human populationsU01DK085545 · NIDDK · UNIVERSITY OF OXFORD · PI CHAN, JULIANA CN, EBRAHIM, SHAH BRIAN · 2009 to 2013
$2.8M
Medical Research Council MC_PC_13049Medical Research Council MC_PC_14135Medical Research Council MC_QA137853Medical Research Council MC_U137686851Medical Research Council MC_UU_12026/2NIDDK NIH HHS U01 DK085545Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bone mineral densityCardiovascular diseaseCausalityCoronary artery diseaseinsulin resistanceMendelian randomizationType 2 diabetesUK biobank

Identifiers

PMID28989980
PMCPMC5606062
OpenAlexW2748934676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.