Evidence map›Paper›PMID 28989976›Full record

ArticleInternational journal of cancer research and molecular mechanisms2017

Hematopoietic Stem Cell-derived Adipocytes Promote Tumor Growth and Cancer Cell Migration.

Y Xiong, D L Russell, L T McDonald, L A Cowart, A C LaRue

Open access · diamondAbstract read
In one paragraph

Article in International journal of cancer research and molecular mechanisms, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Breast Cancer Chemoresistance: Insights into the Regulatory Role of lncRNA.International journal of molecular sciences · 2023
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Cancer-associated adipocytes: emerging supporters in breast cancer.Journal of experimental & clinical cancer research : CR · 2020
    Review
  8. Adipocyte and lipid metabolism in cancer drug resistance.The Journal of clinical investigation · 2019
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Y XiongResearch Services, Ralph H Johnson Veterans Affairs Medical Center, Charleston, South Carolina, USA.
D L RussellResearch Services, Ralph H Johnson Veterans Affairs Medical Center, Charleston, South Carolina, USA.
L T McDonaldResearch Services, Ralph H Johnson Veterans Affairs Medical Center, Charleston, South Carolina, USA.
L A CowartResearch Services, Ralph H Johnson Veterans Affairs Medical Center, Charleston, South Carolina, USA.
A C LaRueResearch Services, Ralph H Johnson Veterans Affairs Medical Center, Charleston, South Carolina, USA.
Medical University of South Carolina · US

Funding

Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Jian Ouyang · 2009 to 2026
$42.7M
Sphingolipids in Diabetic CardiomyopathyR01HL117233 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI COWART, LAUREN ASHLEY · 2014 to 2018
$1.9M
Hematopoietic Stem Cell-Derived Carcinoma Associated Fibroblasts in TumorR01CA148772 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LARUE, AMANDA C. · 2011 to 2015
$1.3M
Sphingolipids in the Pathophysiology of Obesity and DiabetesI01BX000200 · VA · VA VETERANS ADMINISTRATION HOSPITAL · PI COWART, LAUREN ASHLEY · 2009 to 2025
–
BLRD VA I01 BX000200NCI NIH HHS P30 CA138313NCI NIH HHS R01 CA148772NHLBI NIH HHS R01 HL117233
6 · The paper itself

Abstract

Adipocytes, apart from their critical role as the energy storage depots, contribute to the composition of the tumor microenvironment. Our previous studies based on a single hematopoietic stem cell (HSC) transplantation model, have revealed a novel source of adipocytes from HSCs

Indexed as

AdipocyteBreast cancerHematopoietic stem cellMelanomaTumor microenvironment

Identifiers

PMID28989976
PMCPMC5627654
OpenAlexW2624692928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.