Evidence map›Paper›PMID 28989952›Full record

ArticleMaterials today. Communications2017

Synthesis and characterization of thermally responsive N-isopropylacrylamide hydrogels copolymerized with novel hydrophobic polyphenolic crosslinkers.

Shuo Tang, Rohit Bhandari, Sean P Delaney, Eric J Munson, Thomas D Dziubla, J Zach Hilt

Abstract read
In one paragraph

Article in Materials today. Communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Development of NovelGels (Basel, Switzerland) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuo TangDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky 40506, USA.
Rohit BhandariDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky 40506, USA.
Sean P DelaneyDepartment of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40506, USA.
Eric J MunsonDepartment of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40506, USA.
Thomas D DziublaDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky 40506, USA.
J Zach HiltDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky 40506, USA.

Funding

Vascular Mechanisms of PCB-Induced Brain MetastasesP42ES007380 · NIEHS · UNIVERSITY OF KENTUCKY · PI PEARSON, KEVIN JOSEPH · 1997 to 2024
$47.8M
NIEHS NIH HHS P42 ES007380
6 · The paper itself

Abstract

Two series of thermosensitive hydrogels were synthesized by copolymerizing N-isopropylacrylamide (NIPAAm) with various contents of novel hydrophobic crosslinkers, curcumin multiacrylate (CMA) and quercetin multiacrylate (QMA). The compositions of the resulting hydrogels were characterized using solid state-NMR (ss-NMR), and the temperature dependent swelling behavior and lower critical solution temperature (LCST) were characterized using swelling studies and differential scanning calorimetry (DSC). Increasing the crosslinker content resulted in a significant decrease in the LCST and swelling ratio of hydrogels, which could be attributed to the increased hydrophobicity introduced by CMA or QMA. All of the hydrogels demonstrated temperature responsive swelling with the extent of swelling decreasing with increasing crosslinker content. The lower crosslinker content gels displayed sharper phase transitions, while the high crosslinker content gels had broader phase transitions.

Identifiers

PMID28989952
PMCPMC5628756

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.