ReviewIndian journal of endocrinology and metabolism
A Pragmatic Approach to the Indeterminate Thyroid Nodule.
Review in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Developing a tool that could reliably refute total thyroidectomy for solitary Bethesda IV thyroid nodules.Updates in surgery · 2021Article
- Evaluation of the diagnostic performance of contrast-enhanced ultrasound combined withGland surgery · 2021Article
- Review
- Response to the Letter from Drs. Greenstein and Brown.Inflammatory bowel diseases · 2019Article
- Role of Strain Elastography and Shear-Wave Elastography in a Multiparametric Clinical Approach to Indeterminate Cytology Thyroid Nodules.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Indeterminate Thyroid Nodule: Mystery Continues Despite Recent Advances.Indian journal of endocrinology and metabolismArticle
- Role of Genetic Testing in the Management of Indeterminate Thyroid Nodules in the Indian Setting.Indian journal of endocrinology and metabolismReview
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Authors and funding
1 author.
Funding
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Abstract
Thyroid nodules are prevalent in upto 68% of randomly selected individuals in whom high resolution ultrasound is performed. The majority of nodules are benign. The use of ultrasound coupled with FNAC has dramatically reduced the number of patients who undergo surgery for nodules. The six tier Bethesda scoring system has reduced variability and increased the ability to clinicians to guide patients with thyroid nodules. There is good correlation between cytology and histopathologic outcomes. A significant proportion of patients will however fall into an indeterminate category. The availability of molecular markers enhanced with next generation sequencing technology and the expression classifier are added diagnostic aids that can help in management. However these are not available in many countries and in resource limited settings. A pragmatic approach to the diagnosis of indeterminate nodules includes utilising pre and post test probability, clinical acumen, correlation of ultrasound findings and expert opinion in some settings. Using this approach high risk patients can be appropriately chosen for surgery while relegating patients with lower risk to watchful followup.
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