ArticleChemical science2017
Enantioselective
Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Regioselective and site-divergent synthesis of tetrahydropyridines by controlled reductive-oxidative dearomative hydroarylation of pyridinium salts.Nature communications · 2025Article
- Grignard Reagent Addition to Pyridinium Salts: A Catalytic Approach to Chiral 1,4-Dihydropyridines.ACS catalysis · 2024Article
- Recent Strategies in the Nucleophilic Dearomatization of Pyridines, Quinolines, and Isoquinolines.Chemical reviews · 2024Review
- Enantioselective SAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Construction of 1,4-Dihydropyridines: The Evolution of C4 Source.Topics in current chemistry (Cham) · 2023Review
- Recent Progresses in the Catalytic Stereoselective Dearomatization of Pyridines.Molecules (Basel, Switzerland) · 2023Review
- Gold(I)-Catalyzed Nucleophilic Allylation of Azinium Ions with Allylboronates.Angewandte Chemie (International ed. in English) · 2022Article
- NHC Catalysis for Umpolung Pyridinium Alkylation via Deoxy-Breslow Intermediates.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022Article
- NHC Catalysis for Umpolung Pyridinium Alkylation via Deoxy-Breslow Intermediates.Angewandte Chemie (International ed. in English) · 2022Article
- The Role of the Fused Ring in Bicyclic Triazolium Organocatalysts: Kinetic, X-ray, and DFT Insights.The Journal of organic chemistry · 2022Article
- Brønsted acid-enhanced copper-catalyzed atroposelective cycloisomerization to axially chiral arylquinolizones via dearomatization of pyridine.Nature communications · 2022Article
- Catalytic enantioselective synthesis of 1,4-dihydropyridinesChemical science · 2021Article
- Evidence for Simultaneous Dearomatization of Two Aromatic Rings under Mild Conditions in Cu(I)-Catalyzed Direct Asymmetric Dearomatization of Pyridine.Journal of the American Chemical Society · 2020Article
- Regio- and diastereoselective dearomatizations ofChemical science · 2019Article
- A tandem dearomatization/rearomatization strategy: enantioselective N-heterocyclic carbene-catalyzed α-arylation.Chemical science · 2019Article
- Asymmetric Cu-Catalyzed 1,4-Dearomatization of Pyridines and Pyridazines without Preactivation of the Heterocycle or Nucleophile.Journal of the American Chemical Society · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
NHC-catalyzed nucleophilic dearomatization of alkyl pyridiniums has been achieved to generate 1,4-dihydropyridines with high enantioselectivity. This is a rare example of catalytic, asymmetric addition of a nucleophile to the activated pyridinium that prefers C-4 functionalization leading to the 1,4-dihydropyridine with high selectivity.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.