Evidence map›Paper›PMID 28989666›Full record

ArticleChemical science2017

Development of a high quantum yield dye for tumour imaging.

Dan Yang, Huasen Wang, Chengjie Sun, Hui Zhao, Kuan Hu, Weirong Qin, Rui Ma, Feng Yin, Xuan Qin, Qianling Zhang and 2 more

Abstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Dithieno[3,2-RSC advances · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. From Live Cells toACS omega · 2018
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dan YangSchool of Chemical Biology and Biotechnology , Shenzhen Graduate School of Peking University , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn.
Huasen WangDepartment of Materials Science and Engineering , South University of Science and Technology of China , Shenzhen 518055 , China . Email: liangyy@sustc.edu.cn.
Chengjie SunSchool of Chemical Biology and Biotechnology , Shenzhen Graduate School of Peking University , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn.
Hui ZhaoSchool of Chemical Biology and Biotechnology , Shenzhen Graduate School of Peking University , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn.
Kuan HuSchool of Chemical Biology and Biotechnology , Shenzhen Graduate School of Peking University , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn.ORCID 0000-0003-2448-2254
Weirong QinSchool of Chemical Biology and Biotechnology , Shenzhen Graduate School of Peking University , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn.
Rui MaDepartment of Materials Science and Engineering , South University of Science and Technology of China , Shenzhen 518055 , China . Email: liangyy@sustc.edu.cn.
Feng YinSchool of Chemical Biology and Biotechnology , Shenzhen Graduate School of Peking University , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn.ORCID 0000-0001-7407-9047
Xuan QinSchool of Chemical Biology and Biotechnology , Shenzhen Graduate School of Peking University , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn.
Qianling ZhangShenzhen Key Laboratory of Functional Polymer , College of Chemistry and Environmental Engineering , Shenzhen University , Shenzhen , Guangdong 518060 , China.
Yongye LiangDepartment of Materials Science and Engineering , South University of Science and Technology of China , Shenzhen 518055 , China . Email: liangyy@sustc.edu.cn.
Zigang LiSchool of Chemical Biology and Biotechnology , Shenzhen Graduate School of Peking University , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A fluorescent dye, FEB, with high fluorescence quantum yield for tumour imaging is reported. FEB dyes can be efficiently synthesized in three steps and then easily modified with either PEG or PEG-iRGD to yield FEB-2000 or FEB-2000-iRGD, respectively. Both modified dyes showed negligible toxicity and were thus able to be adopted for

Identifiers

PMID28989666
PMCPMC5628574

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.