Evidence map›Paper›PMID 28989659›Full record

ArticleChemical science2017

A multi-signal fluorescent probe for simultaneously distinguishing and sequentially sensing cysteine/homocysteine, glutathione, and hydrogen sulfide in living cells.

Longwei He, Xueling Yang, Kaixin Xu, Xiuqi Kong, Weiying Lin

Abstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. A pyrene-based fluorescent probe for HPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  3. Review
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  12. Article
  13. Review
  14. Fluorescent Probes for Live Cell Thiol Detection.Molecules (Basel, Switzerland) · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Longwei HeInstitute of Fluorescent Probes for Biological Imaging , School of Chemistry and Chemical Engineering , School of Materials Science and Engineering , University of Jinan , Shandong 250022 , P. R. China . Email: weiyinglin2013@163.com.ORCID 0000-0002-8206-8783
Xueling YangInstitute of Fluorescent Probes for Biological Imaging , School of Chemistry and Chemical Engineering , School of Materials Science and Engineering , University of Jinan , Shandong 250022 , P. R. China . Email: weiyinglin2013@163.com.
Kaixin XuInstitute of Fluorescent Probes for Biological Imaging , School of Chemistry and Chemical Engineering , School of Materials Science and Engineering , University of Jinan , Shandong 250022 , P. R. China . Email: weiyinglin2013@163.com.
Xiuqi KongInstitute of Fluorescent Probes for Biological Imaging , School of Chemistry and Chemical Engineering , School of Materials Science and Engineering , University of Jinan , Shandong 250022 , P. R. China . Email: weiyinglin2013@163.com.ORCID 0000-0003-0478-7982
Weiying LinInstitute of Fluorescent Probes for Biological Imaging , School of Chemistry and Chemical Engineering , School of Materials Science and Engineering , University of Jinan , Shandong 250022 , P. R. China . Email: weiyinglin2013@163.com.ORCID 0000-0001-8080-4102

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biothiols, which have a close network of generation and metabolic pathways among them, are essential reactive sulfur species (RSS) in the cells and play vital roles in human physiology. However, biothiols possess highly similar chemical structures and properties, resulting in it being an enormous challenge to simultaneously discriminate them from each other. Herein, we develop a unique fluorescent probe (

Identifiers

PMID28989659
PMCPMC5628385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.