Evidence map›Paper›PMID 28989651›Full record

ArticleChemical science2017

Fluorometric probing of the lipase level as acute pancreatitis biomarkers based on interfacially controlled aggregation-induced emission (AIE).

Jie Shi, Qianchun Deng, Chuyun Wan, Mingming Zheng, Fenghong Huang, Bo Tang

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 97 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jie ShiHubei Key Laboratory of Lipid Chemistry and Nutrition , Oil Crops and Lipids Process Technology National & Local Joint Engineering Laboratory , Key Laboratory of Oilseeds Processing , Ministry of Agriculture , Oil Crops Research Institute , Chinese Academy of Agricultural Sciences , Wuhan 430062 , China . Email: shij@whu.edu.cn.ORCID 0000-0001-9521-3073
Qianchun DengHubei Key Laboratory of Lipid Chemistry and Nutrition , Oil Crops and Lipids Process Technology National & Local Joint Engineering Laboratory , Key Laboratory of Oilseeds Processing , Ministry of Agriculture , Oil Crops Research Institute , Chinese Academy of Agricultural Sciences , Wuhan 430062 , China . Email: shij@whu.edu.cn.
Chuyun WanHubei Key Laboratory of Lipid Chemistry and Nutrition , Oil Crops and Lipids Process Technology National & Local Joint Engineering Laboratory , Key Laboratory of Oilseeds Processing , Ministry of Agriculture , Oil Crops Research Institute , Chinese Academy of Agricultural Sciences , Wuhan 430062 , China . Email: shij@whu.edu.cn.
Mingming ZhengHubei Key Laboratory of Lipid Chemistry and Nutrition , Oil Crops and Lipids Process Technology National & Local Joint Engineering Laboratory , Key Laboratory of Oilseeds Processing , Ministry of Agriculture , Oil Crops Research Institute , Chinese Academy of Agricultural Sciences , Wuhan 430062 , China . Email: shij@whu.edu.cn.
Fenghong HuangHubei Key Laboratory of Lipid Chemistry and Nutrition , Oil Crops and Lipids Process Technology National & Local Joint Engineering Laboratory , Key Laboratory of Oilseeds Processing , Ministry of Agriculture , Oil Crops Research Institute , Chinese Academy of Agricultural Sciences , Wuhan 430062 , China . Email: shij@whu.edu.cn.
Bo TangCollege of Chemistry , Chemical Engineering and Materials Science , Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong , Key Laboratory of Molecular and Nano Probes , Ministry of Education , Shandong Normal University , Jinan 250014 , China . Email: tangb@sdnu.edu.cn.ORCID 0000-0002-8712-7025
Indian Institute of Oilseeds Research · INShandong Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a sudden inflammation of the pancreas, acute pancreatitis presents severe complications and a high mortality rate, despite treatment. Lipase in serum serves as an essential biomarker of acute pancreatitis and even pancreatic cancer. Therefore, developing robust, convenient and sensitive probing of lipase levels is greatly needed. In this work, we present glutamate functionalized tetraphenylethylene (TPE) as a "turn-on" fluorescent probe (

Identifiers

PMID28989651
PMCPMC5628346
OpenAlexW2722664776

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.