Evidence map›Paper›PMID 28989217›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2017

Epi-direction detected multimodal imaging of an unstained mouse retina with a Yb-fiber laser.

Gabrielle A Murashova, Christopher A Mancuso, Sanae Sakami, Krzysztof Palczewski, Grazyna Palczewska, Marcos Dantus

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gabrielle A MurashovaDepartment of Chemistry, Michigan State University, East Lansing, MI, 48824, USA.
Christopher A MancusoDepartment of Chemistry, Michigan State University, East Lansing, MI, 48824, USA.
Sanae SakamiDepartment of Pharmacology, Case Western Reserve University, Cleveland OH 44106, USA.
Krzysztof PalczewskiDepartment of Pharmacology, Case Western Reserve University, Cleveland OH 44106, USA.
Grazyna PalczewskaDepartment of Medical Devices, Polgenix Inc., Cleveland, OH 44106, USA.
Marcos DantusDepartment of Chemistry, Michigan State University, East Lansing, MI, 48824, USA.

Funding

A two-photon ophthalmoscope for human retinal imaging and functional testingU01EY025451 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI PALCZEWSKI, KRZYSZTOF · 2015 to 2019
$3.2M
NEI NIH HHS U01 EY025451
6 · The paper itself

Abstract

In this work, we present all epi-direction detected images of an unstained mouse retina using multiphoton microscopy with a sub-50 fs Yb-fiber laser centered at 1.07 μm. This wavelength is particularly interesting as the fundamental wavelength is transparent to the anterior segment of the eye and the higher harmonics are above DNA-damaging UV wavelengths. We present a characterization of the multimodal signals emitted from the different retinal layers, as well as from the choroid and the sclera. By characterizing native multiphoton signals from the retina, we move closer to having Yb-fiber considered for

Indexed as

Biomedical imagingJenLab Young Investigator AwardMultimodalRetinaSecond Harmonic GenerationUltrafast lasersYb-fiber Laser

Identifiers

PMID28989217
PMCPMC5627661

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.