Evidence map›Paper›PMID 28988986›Full record

ArticleStem cell reports2017

Phosphorylation of Threonine

Xianmixinuer Abulaiti, Han Zhang, Aifang Wang, Na Li, Yang Li, Chenchen Wang, Xiaojuan Du, Lingsong Li

Open access · goldAbstract read
In one paragraph

Article in Stem cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Regulation of Embryonic Stem Cell Self-Renewal.Life (Basel, Switzerland) · 2022
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Xianmixinuer AbulaitiDepartment of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Han ZhangShanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Aifang WangShanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Na LiShanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Yang LiDepartment of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Chenchen WangDepartment of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China; Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: wangcc@sari.ac.cn.
Xiaojuan DuDepartment of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Lingsong LiDepartment of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China; Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: lils@sari.ac.cn.
Peking University · CNChinese Academy of Sciences · CNUniversity of Chinese Academy of Sciences · CNShanghaiTech University · CN

Funding

Corticostriatal networks and NMDAR mediation of habitual and flexible actionK22AA020303 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BRIGMAN, JONATHAN L · 2011 to 2013
$486k
NIAAA NIH HHS K22 AA020303
6 · The paper itself

Abstract

OCT4 is required to maintain the pluripotency of embryonic stem cells (ESCs); yet, overdose-expression of OCT4 induces ESC differentiation toward primitive endoderm. The molecular mechanism underlying this differentiation switch is not fully understood. Here, we found that substitution of threonine

Indexed as

Cell DifferentiationProtein Processing, Post-TranslationalAmino Acid SubstitutionAnimalsCells, CulturedMiceMouse Embryonic Stem CellsOctamer Transcription Factor-3PhosphorylationProtein BindingSOXB1 Transcription FactorsThreonineOctamer Transcription Factor-3Pou5f1 protein, mouseSox2 protein, mouseSOXB1 Transcription FactorsThreonineembryonic developmentESC pluripotencygenome editinglineage specificationOCT4-phosphorylationprotein interactionSOX17SOX2

Identifiers

PMID28988986
PMCPMC5829306
OpenAlexW2762022687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.