ReviewSeminars in perinatology2017
Prevention of preterm birth: Novel interventions for the cervix.
Review in Seminars in perinatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Associations of Cervical Features and Preventive Interventions With Gestational Age at Delivery.Cureus · 2026Article
- Comparative Effectiveness of Pessary Placement, Cervical Cerclage, or Expectant Management in Preventing Preterm Delivery in Twin Pregnancies.Journal of personalized medicine · 2026Article
- Stabilization of cervical stiffness associated with cervical pessary placement in women at risk for preterm birth.PloS one · 2026Observational
- The Lioness™ device: a prospective non-randomized safety and feasibility study of a novel device for preterm birth delay and prevention.BMC pregnancy and childbirth · 2025Article
- Predicting preterm birth using auto-ML frameworks: a large observational study using electronic inpatient discharge data.Frontiers in pediatrics · 2024Article
- Bioengineering and the cervix: The past, current, and future for addressing preterm birth.Current research in physiology · 2023Review
- Next generation strategies for preventing preterm birth.Advanced drug delivery reviews · 2021Review
- Emergency Cervical Cerclage.Journal of clinical medicine · 2021Review
- Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Preterm birth is the leading cause of neonatal mortality and morbidity worldwide. Spontaneous preterm birth is a complex, multifactorial condition in which cervical dysfunction plays an important role in some women. Current treatment options for cervical dysfunction include cerclage and supplemental progesterone. In addition, cervical pessary is being studied in research protocols. However, cerclage, supplemental progesterone and cervical pessary have well known limitations and there is a strong need for alternate treatment options. In this review, we discuss two novel interventions to treat cervical dysfunction: (1) injectable, silk protein-based biomaterials for cervical tissue augmentation (injectable cerclage) and (2) a patient-specific pessary. Three-dimensional computer simulation of the cervix is performed to provide a biomechanical rationale for the interventions. Further development of these novel interventions could lead to new treatment options for women with cervical dysfunction.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.