Evidence map›Paper›PMID 28988577›Full record

ReviewAlcohol research : current reviews2017

Pathophysiology of the Effects of Alcohol Abuse on the Endocrine System.

Nadia Rachdaoui, Dipak K Sarkar

Open access · greenAbstract readReview
In one paragraph

Review in Alcohol research : current reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it, 165 citations in OpenAlex.

  1. Alcohol consumption and heart failure: a dose-response meta-analysis.The Cochrane database of systematic reviews · 2024
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nadia RachdaouiNadia Rachdaoui, Ph.D., is an Assistant Research Professor, and Dipak K. Sarkar, Ph.D., D.Phil., is Board of Governors Distinguished Professor, in the Rutgers Endocrine Research Program, Department of Animal Sciences, Rutgers University, New Brunswick, New Jersey.
Dipak K SarkarNadia Rachdaoui, Ph.D., is an Assistant Research Professor, and Dipak K. Sarkar, Ph.D., D.Phil., is Board of Governors Distinguished Professor, in the Rutgers Endocrine Research Program, Department of Animal Sciences, Rutgers University, New Brunswick, New Jersey.
Rutgers Sexual and Reproductive Health and Rights · NL

Funding

ALCOHOL AND HYPERPROLACTINEMIAR01AA011591 · NIAAA · WASHINGTON STATE UNIVERSITY · PI SARKAR, DIPAK KUMAR · 1998 to 2022
$5.0M
Role of Opiates in Alcohol-Induced Neurotoxicity- Diversity supplementR37AA008757 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI SARKAR, DIPAK KUMAR · 2009 to 2018
$4.0M
Fetal alcohol, estrogen-regulated genes and prostate cancerR21AA024330 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI SARKAR, DIPAK KUMAR · 2015 to 2016
$407k
NIAAA NIH HHS R01 AA011591NIAAA NIH HHS R21 AA024330NIAAA NIH HHS R37 AA008757
6 · The paper itself

Abstract

Alcohol can permeate virtually every organ and tissue in the body, resulting in tissue injury and organ dysfunction. Considerable evidence indicates that alcohol abuse results in clinical abnormalities of one of the body's most important systems, the endocrine system. This system ensures proper communication between various organs, also interfacing with the immune and nervous systems, and is essential for maintaining a constant internal environment. The endocrine system includes the hypothalamic-pituitary-adrenal axis, the hypothalamic-pituitary-gonadal axis, the hypothalamic-pituitary-thyroid axis, the hypothalamic-pituitary-growth hormone/insulin-like growth factor-1 axis, and the hypothalamic-posterior pituitary axis, as well as other sources of hormones, such as the endocrine pancreas and endocrine adipose tissue. Alcohol abuse disrupts all of these systems and causes hormonal disturbances that may result in various disorders, such as stress intolerance, reproductive dysfunction, thyroid problems, immune abnormalities, and psychological and behavioral disorders. Studies in both humans and animal models have helped shed light on alcohol's effects on various components of the endocrine system and their consequences.

Indexed as

AlcoholismAnimalsEndocrine SystemEthanolHumansHypothalamo-Hypophyseal SystemImmune SystemPituitary-Adrenal SystemEthanol

Identifiers

PMID28988577
PMCPMC5513689
OpenAlexW2607504788

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.