Evidence map›Paper›PMID 28988576›Full record

ReviewAlcohol research : current reviews2017

Alcohol and the Lung.

Ashish J Mehta, David M Guidot

Open access · greenAbstract readReview
PubMed Full text at PMC
In one paragraph

Review in Alcohol research : current reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. The alcohol exposome.Alcohol (Fayetteville, N.Y.) · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Molecular Imaging of Pulmonary Inflammation in Users of Electronic and Combustible Cigarettes: A Pilot Study.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ashish J MehtaAshish J. Mehta, M.D., is an Assistant Professor of Medicine in the Department of Medicine, Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Emory University, Atlanta, Georgia, and a Staff Physician at the Atlanta VA Medical Center, Decatur, Georgia. David M. Guidot, M.D., is a Professor of Medicine in the Department of Medicine, Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Emory University, Atlanta, Georgia, and a Staff Physician at the Atlanta VA Medical Center, Decatur, Georgia.
David M GuidotAshish J. Mehta, M.D., is an Assistant Professor of Medicine in the Department of Medicine, Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Emory University, Atlanta, Georgia, and a Staff Physician at the Atlanta VA Medical Center, Decatur, Georgia. David M. Guidot, M.D., is a Professor of Medicine in the Department of Medicine, Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Emory University, Atlanta, Georgia, and a Staff Physician at the Atlanta VA Medical Center, Decatur, Georgia.
Atlanta VA Medical Center · US

Funding

HIV-induced redox stress and the alveolar macrophage as a resistant reservoirR01HL125042 · NHLBI · EMORY UNIVERSITY · PI BROWN, LOU ANN S, GUIDOT, DAVID MARSHALL · 2014 to 2017
$2.8M
Zinc deficiency in the alcoholic lungR01AA017627 · NIAAA · EMORY UNIVERSITY · PI GUIDOT, DAVID MARSHALL, JOSHI, PRATIBHA C · 2010 to 2014
$1.3M
CSRD VA IK2 CX000643NHLBI NIH HHS R01 HL125042NIAAA NIH HHS R01 AA017627
6 · The paper itself

Abstract

Among the many organ systems affected by harmful alcohol use, the lungs are particularly susceptible to infections and injury. The mechanisms responsible for rendering people with alcohol use disorder (AUD) vulnerable to lung damage include alterations in host defenses of the upper and lower airways, disruption of alveolar epithelial barrier integrity, and alveolar macrophage immune dysfunction. Collectively, these derangements encompass what has been termed the "alcoholic lung" phenotype. Alcohol-related reductions in antioxidant levels also may contribute to lung disease in people with underlying AUD. In addition, researchers have identified several regulatory molecules that may play crucial roles in the alcohol-induced disease processes. Although there currently are no approved therapies to combat the detrimental effects of chronic alcohol consumption on the respiratory system, these molecules may be potential therapeutic targets to guide future investigation.

Indexed as

Alcohol-Related DisordersAnimalsHumansLung Diseases

Identifiers

PMID28988576
PMCPMC5513688
OpenAlexW2606462399

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.