ArticleEpidemiology and psychiatric sciences2019
Childhood abuse and psychotic experiences - evidence for mediation by adulthood adverse life events.
Article in Epidemiology and psychiatric sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Exploring the roots of schizophrenia: Current research and future directions (Review).Experimental and therapeutic medicine · 2026Review
- Impact of childhood trauma and parental socialization on at-risk mental state in non-clinical adolescents.World journal of psychiatry · 2025Article
- Insomnia and depressive symptoms mediate childhood abuse and psychotic experience of male juvenile offenders: a chain mediation model.BMC psychology · 2025Article
- Article
- Association of physical and sexual assault with mortality in two British birth cohorts.BMJ public health · 2024Article
- Independent effects of early life adversity on social cognitive function in patients with schizophrenia.Frontiers in psychiatry · 2024Article
- The relationship between interpersonal violence in adulthood and mental health: a longitudinal study based on the Northern Swedish Cohort.BMC public health · 2023Article
- Erroneous Thought in Inpatients with Major Depressive Disorder: The Role of Psychological Trauma During Childhood and Adulthood.Neuropsychiatric disease and treatment · 2023Article
- Mediating role of impaired wisdom in the relation between childhood trauma and psychotic-like experiences in Chinese college students: a nationwide cross-sectional study.BMC psychiatry · 2022Article
- Review
- The clinical characterization of the patient with primary psychosis aimed at personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021Article
- ResilienCity: Resilience and Psychotic-Like Experiences 10 Years After L'Aquila Earthquake.Frontiers in psychiatry · 2020Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
aimsWe have previously reported an association between childhood abuse and psychotic experiences (PEs) in survey data from South East London. Childhood abuse is related to subsequent adulthood adversity, which could form one pathway to PEs. We aimed to investigate evidence of mediation of the association between childhood abuse and PEs by adverse life events.
methodsData were analysed from the South East London Community Health Study (SELCoH, n = 1698). Estimates of the total effects on PEs of any physical or sexual abuse while growing up were partitioned into direct (i.e. unmediated) and indirect (total and specific) effects, mediated via violent and non-violent life events.
resultsThere was strong statistical evidence for direct (OR 1.58, 95% CI: 1.19-2.1) and indirect (OR 1.51, 95% CI: 1.32-1.72) effects of childhood abuse on PEs after adjustment for potential confounders, indicating partial mediation of this effect via violent and non-violent life events. An estimated 47% of the total effect of abuse on PEs was mediated via adulthood adverse life events, of which violent life events made up 33% and non-violent life events the remaining 14%.
conclusionsThe association between childhood abuse and PEs is partly mediated through the experience of adverse life events in adulthood. There is some evidence that a larger proportion of this effect was mediated through violent life events than non-violent life events.
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