Evidence map›Paper›PMID 28988412›Full record

Trial reportPediatric blood & cancer2018

Cognitive outcomes among Latino survivors of childhood acute lymphoblastic leukemia and lymphoma: A cross-sectional cohort study using culturally competent, performance-based assessment.

Laura Bava, Alexis Johns, Kimberly Kayser, David R Freyer

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Pediatric blood & cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Prenatal socioeconomic status and social support are associated with neonatal brain morphology, toddler language and psychiatric symptoms.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2020
    Article
  6. Article
  7. Exploring Differences in Perceived Satisfaction, Resilience, and Achievement Between Hispanic and Non-Hispanic White Childhood Cancer Survivors.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Laura BavaSurvivorship and Supportive Care Program, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, California.ORCID http://orcid.org/0000-0001-6183-2423
Alexis JohnsDepartment of Plastic and Maxillofacial Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California.
Kimberly KayserSurvivorship and Supportive Care Program, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, California.
David R FreyerDepartment of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California.ORCID http://orcid.org/0000-0001-5280-990X
University of Southern California · USChildren's Hospital of Los Angeles · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MYLES G COCKBURN · 1985 to 2026
$181.4M
NCI NIH HHS P30 CA014089
6 · The paper itself

Abstract

backgroundThis study sought to characterize cognitive outcomes among Latino survivors of childhood acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LL). PROCEDURE: In this cross-sectional cohort study, Latino survivors of ALL (n = 57) and LL (n = 5) aged 6-16 years were pooled and evaluated using validated measures of cognitive, academic, and behavioral function and English language proficiency. Performance was compared with norms using single-sample t-tests.

resultsIn this cohort (n = 62, 50% male), mean ages at diagnosis and testing were 4.5 and 10.8 years, respectively; mean time off treatment was 44.7 months. All participants spoke English and over half (57%) identified Spanish as the primary language in the home. Forty-two families (68%) placed in the two lowest Hollingshead socioeconomic status categories. Participants were below average for working memory (P < 0.001). Overall, participants were in the average range, but significantly lower than published norms on domain-specific measures of verbal comprehension (P < 0.001); perceptual reasoning (P = 0.033); processing speed (P = 0.003); visual memory (P < 0.001); visuomotor attention, scanning, and sequencing (P = 0.005); and reading comprehension (P = 0.001). Parents reported concerns with working memory (P < 0.001) and metacognition (P = 0.014).

conclusionsSimilar to other childhood ALL/LL survivors, overall cognitive function in this Latino sample was relatively preserved but selected deficits were observed. Routine cognitive screening is indicated in this population.

Indexed as

Cancer SurvivorsCognitionCognition DisordersHispanic or LatinoPrecursor Cell Lymphoblastic Leukemia-LymphomaAdolescentAge of OnsetChildCross-Sectional StudiesFemaleHumansMaleacute lymphoblastic leukemiacancercognitivelate effectsLatinosociodemographics

Identifiers

PMID28988412
PMCPMC7521146
OpenAlexW2760990181

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.