Evidence map›Paper›PMID 28988402›Full record

ArticleInternational orthopaedics2018

Nutritional markers may identify patients with greater risk of re-admission after geriatric hip fractures.

Austin V Stone, Alexander Jinnah, Brian J Wells, Hal Atkinson, Anna N Miller, Wendell M Futrell, Kristin Lenoir, Cynthia L Emory

Abstract read
In one paragraph

Article in International orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  7. Males Have Higher Rates of Peri-operative Mortality Following Surgery for Osteoporotic Vertebral Compression Fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Austin V StoneDivision of Sports Medicine, Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Alexander JinnahDepartment of Orthopaedic Surgery, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA. ajinnah@wakehealth.edu.
Brian J WellsTranslational Science Institute, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Hal AtkinsonGerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Anna N MillerDepartment of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Wendell M FutrellTranslational Science Institute, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Kristin LenoirTranslational Science Institute, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Cynthia L EmoryDepartment of Orthopaedic Surgery, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
NCATS NIH HHS UL1 TR001420
6 · The paper itself

Abstract

purposeOsteoporotic hip fractures are increasing in prevalence with the growing elderly population. Morbidity and mortality remain high following osteoporotic hip fractures despite advances in medical and surgical treatments. The associated costs and medical burdens are increased with a re-admission following hip fracture treatment. This study sought to identify demographic and clinical values that may be a predictive model for 30-day re-admission risk following operative management of an isolated hip fracture.

methodsBetween January 1, 2013 and April 30, 2015 all patients admitted to a single academic medical centre for treatment of a hip fracture were reviewed. Candidate variables included standard demographics, common laboratory values, and markers of comorbid conditions and nutrition status. A 30-day, all-cause re-admission model was created utilizing multivariate logistic regression.

resultsA total of 607 patients with hip fractures were identified and met the inclusion criteria; of those patients, 67 were re-admitted within 30 days. Univariate analysis indicates that the re-admission group had more comorbidities (p < 0.001) and lower albumin (p = 0.038) and prealbumin (p < 0.001). The final, reduced model contained 12 variables and incorporated four out of five nutritional makers with an internally, cross-validated C-statistic of 0.811 (95% CI: 0.754, 0.867).

conclusionOur results indicate that specific nutritional laboratory markers at the index admission may identify patients that have a greater risk of re-admission after hip fracture. This model identifies potentially modifiable risk factors and may allow orthogeriatricians to better educate patients and better treat post-operative nutritional status and care.

Indexed as

Nutritional StatusAgedAged, 80 and overBiomarkersComorbidityFemaleHip FracturesHumansLogistic ModelsMaleOsteoporotic FracturesPatient ReadmissionPostoperative PeriodRisk AssessmentRisk FactorsROC CurveBiomarkersElectronic medical recordsHip fracturePredictionRe-admissionRisk factors

Identifiers

PMID28988402
PMCPMC9235009

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.