Evidence map›Paper›PMID 28988117›Full record

ArticleThe Journal of investigative dermatology2018

Mas-Related G-Protein Coupled Receptors and Cowhage-Induced Itch.

Vemuri B Reddy, Ehsan Azimi, Lei Chu, Ethan A Lerner

Abstract readLetter
In one paragraph

Article in The Journal of investigative dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Punctate Administration of Ficin as a human and animal model of non-histaminergic itch.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
    Article
  6. Article
  7. Frontiers in molecular neuroscience · 2022
    Review
  8. Observational
  9. Article
  10. MRGPRX4 in Cholestatic Pruritus.Seminars in liver disease · 2021
    Review
  11. Article
  12. Itch in Hymenoptera Sting Reactions.Frontiers in allergy · 2021
    Article
  13. Physiology and Pathophysiology of Itch.Physiological reviews · 2020
    Review
  14. Article
  15. Neural processing of itch.Neuroscience · 2013
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vemuri B ReddyCutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital/Harvard Medical School, Charlestown, Massachusetts, USA.
Ehsan AzimiCutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital/Harvard Medical School, Charlestown, Massachusetts, USA.
Lei ChuCutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital/Harvard Medical School, Charlestown, Massachusetts, USA.
Ethan A LernerCutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital/Harvard Medical School, Charlestown, Massachusetts, USA. Electronic address: ELERNER@mgh.harvard.edu.

Funding

Itch, proteases and protease-activated receptorsR01AR057744 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LERNER, ETHAN A · 2010 to 2014
$1.9M
Montagna Symposium on the Biology of SkinR13AR009431 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI SANCY ANN LEACHMAN · 1986 to 2026
$785k
The role of Mrgprs in substance P-induced itchR21AR067399 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LERNER, ETHAN A · 2015 to 2016
$489k
NIAMS NIH HHS R01 AR057744NIAMS NIH HHS R13 AR009431NIAMS NIH HHS R21 AR067399
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell DegranulationCysteine ProteasesHEK293 CellsHistamineHumansMast CellsMucunaNerve Tissue ProteinsPlant ProteinsPruritusReceptors, G-Protein-CoupledReceptors, NeuropeptideSignal TransductionSkinCysteine ProteasesHistaminemas-related gene-X1 receptor, humanMRGPRX2 protein, humanNerve Tissue ProteinsPlant ProteinsReceptors, G-Protein-CoupledReceptors, Neuropeptide

Identifiers

PMID28988117
PMCPMC5794532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.