Evidence map›Paper›PMID 28988060›Full record

ArticleTrends in neurosciences2017

Chandelier Cells Illuminate Inhibitory Control of Prefrontal-Amygdala Outputs.

Thomas F Giustino, Stephen Maren

Abstract readComment
In one paragraph

Article in Trends in neurosciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Thomas F GiustinoDepartment of Psychology and Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA. Electronic address: https://twitter.com/TomGiustino.
Stephen MarenDepartment of Psychology and Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA. Electronic address: maren@tamu.edu.

Funding

Neural Substrates of Contextual Memory in Fear ExtinctionR01MH065961 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MAREN, STEPHEN · 2003 to 2025
$7.9M
Noradrenergic modulation of stress-induced deficits in fear extinctionF31MH112208 · NIMH · TEXAS A&M UNIVERSITY · PI GIUSTINO, THOMAS · 2017 to 2018
$68k
NIMH NIH HHS F31 MH112208NIMH NIH HHS R01 MH065961
6 · The paper itself

Abstract

Inhibitory interneurons comprise a diverse subpopulation of cells that are critical to circuit function. How distinct inhibitory microcircuits control long-range projections remains poorly understood. A recent study by Lu and colleagues uncovered a unidirectional microcircuit of prefrontal chandelier cells that preferentially innervate and suppress long-range amygdala-projecting pyramidal cells.

Indexed as

AmygdalaInterneuronsNeuronsPyramidal CellsSynaptic Transmissionamygdalainterneuronsmicrocircuitsprelimibic

Identifiers

PMID28988060
PMCPMC5685662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.