Evidence map›Paper›PMID 28987476›Full record

ReviewImmunology letters2017

The MAIT conundrum - how human MAIT cells distinguish bacterial colonization from infection in mucosal barrier tissues.

Julia D Berkson, Martin Prlic

Abstract readReview
In one paragraph

Review in Immunology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Multiomic analysis reveals decidual-specific transcriptional programing of MAIT cells.American journal of reproductive immunology (New York, N.Y. : 1989) · 2021
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. A Uniquely Altered Oral Microbiome Composition Was Observed in Pregnant Rats WithFrontiers in cellular and infection microbiology · 2020
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Julia D BerksonVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Martin PrlicVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Seattle, WA 98195, USA. Electronic address: mprlic@fhcrc.org.

Funding

TRAINING IN MOLECULAR AND CELLULAR BIOLOGYT32GM007270 · NIGMS · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 1985 to 2020
$21.0M
Paving the Way for a Novel Therapeutic Approach to Combat HIVDP2DE023321 · NIDCR · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PRLIC, MARTIN · 2012 to 2014
$2.9M
NIDCR NIH HHS DP2 DE023321NIGMS NIH HHS T32 GM007270
6 · The paper itself

Abstract

We review the recent human mucosal-associated invariant T (MAIT) cell literature to examine the signals that control MAIT cell activation. We discuss these signals in context of MAIT cell function in mucosal barrier tissues and address how MAIT cells avoid responding to commensal bacteria, while maintaining responsiveness to infections.

Indexed as

AnimalsBacterial InfectionsCytokinesDiagnosis, DifferentialHomeostasisHumansImmune ToleranceImmunity, InnateMucosal-Associated Invariant T CellsMucous MembraneCytokinesBarrier tissueCommensal bacteriaCytokineEffector functionInfectionMucosal-associated invariant T cell (MAIT)T cell receptor

Identifiers

PMID28987476
PMCPMC5685889

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.