Evidence map›Paper›PMID 28987374›Full record

ArticleJournal of food and drug analysis2017

Exploration of ethyl anthranilate-loaded monolithic matrix-type prophylactic polymeric patch.

Johirul Islam, Kamaruz Zaman, Srijita Chakrabarti, Nilutpal Sharma Bora, Manash Pratim Pathak, Santa Mandal, Julfikar Ali Junejo, Pronobesh Chattopadhyay

Open access · hybridAbstract read
In one paragraph

Article in Journal of food and drug analysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Johirul IslamDivision of Pharmaceutical Technology, Defence Research Laboratory, Tezpur, Assam, India.
Kamaruz ZamanDepartment of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, India.
Srijita ChakrabartiDivision of Pharmaceutical Technology, Defence Research Laboratory, Tezpur, Assam, India.
Nilutpal Sharma BoraDivision of Pharmaceutical Technology, Defence Research Laboratory, Tezpur, Assam, India.
Manash Pratim PathakDivision of Pharmaceutical Technology, Defence Research Laboratory, Tezpur, Assam, India.
Santa MandalDivision of Pharmaceutical Technology, Defence Research Laboratory, Tezpur, Assam, India.
Julfikar Ali JunejoDepartment of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, India.
Pronobesh ChattopadhyayDivision of Pharmaceutical Technology, Defence Research Laboratory, Tezpur, Assam, India.
Defence Research Laboratory · INDibrugarh University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compromised stability of pharmaceutical formulations loaded with volatiles is a serious problem associated with devices designed to deliver volatile compounds. The present study has been focused to evaluate the stability potential of matrix-type polymeric patches composed of volatile ethyl anthranilate for prophylaxis against vector-borne diseases. Ethyl anthranilate-loaded matrix-type polymeric patches were fabricated by solvent evaporation method on an impermeable backing membrane and attached to temporary release liners. Stability testing of the polymeric patches was performed as per the International Conference on Harmonization (ICH) guidelines for 6 months under accelerated conditions. In addition, the quantification of residual solvents was also performed as per the ICH guidelines. After conducting the stability studies for 6 months, the optimized patches showed the best possible results with respect to uniformity of drug content, physical appearance, and other analytical parameters. Furthermore, the amount of residual solvent was found well below the accepted limit. Thus, the present report outlined the analytical parameters to be evaluated to ensure the stability of a certain devices consisting of volatile compounds.

Indexed as

Drug CarriersDrug Delivery SystemsDrug Stabilityortho-AminobenzoatesPharmaceutical PreparationsPolymersDrug Carriersethyl anthranilateortho-AminobenzoatesPharmaceutical PreparationsPolymersControlled releaseEthyl 2-aminobenzoateICH guidelinesInsect repellentPolymeric patch

Identifiers

PMID28987374
PMCPMC9328865
OpenAlexW2557789808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.