Evidence map›Paper›PMID 28987000›Full record

ArticleClinical and experimental immunology2018

MicroRNA-126 deficiency enhanced the activation and function of CD4

F Chu, Y Hu, Y Zhou, M Guo, J Lu, W Zheng, H Xu, J Zhao, L Xu

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. The Regulatory Effects of MicroRNAs on Tumor Immunity.BioMed research international · 2022
    Review
  7. Article
  8. The RecombinantFrontiers in immunology · 2022
    Article
  9. Genome-Wide miRNA Expression Profiling of Molecular Subgroups of Peripheral T-cell Lymphoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. ncRNAs in Type-2 Immunity.Non-coding RNA · 2020
    Review
  15. Review
  16. Functional Role of MicroRNAs in Thymocyte Development.International archives of allergy and immunology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

F ChuSpecial Key Laboratory of Gene Detection and Therapy of Guizhou Provincial Education Department, Guizhou, China.ORCID 0000-0002-8362-4622
Y HuSpecial Key Laboratory of Gene Detection and Therapy of Guizhou Provincial Education Department, Guizhou, China.
Y ZhouDepartment of Medical Physics, Zunyi Medical College, Guizhou, China.
M GuoSpecial Key Laboratory of Gene Detection and Therapy of Guizhou Provincial Education Department, Guizhou, China.
J LuSpecial Key Laboratory of Gene Detection and Therapy of Guizhou Provincial Education Department, Guizhou, China.
W ZhengSpecial Key Laboratory of Gene Detection and Therapy of Guizhou Provincial Education Department, Guizhou, China.
H XuSpecial Key Laboratory of Gene Detection and Therapy of Guizhou Provincial Education Department, Guizhou, China.
J ZhaoSpecial Key Laboratory of Gene Detection and Therapy of Guizhou Provincial Education Department, Guizhou, China.
L XuSpecial Key Laboratory of Gene Detection and Therapy of Guizhou Provincial Education Department, Guizhou, China.
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence has shown that microRNA-126 (miR-126) has been involved in the development and function of immune cells, which contributed to the pathogenesis of related clinical diseases. However, the potential role of miR-126 in the development and function of CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesCells, CulturedColitisDextran SulfateDisease Models, AnimalFemaleHumansInsulin Receptor Substrate ProteinsLymphocyte ActivationMiceMice, Inbred StrainsMice, KnockoutMicroRNAsSignal TransductionDextran SulfateInsulin Receptor Substrate ProteinsIrs1 protein, mouseMicroRNAsMIRN126 microRNA, mouseCD4+ T cellcytokinesDSSIRS-1miR-126

Identifiers

PMID28987000
PMCPMC5758368
OpenAlexW2762728957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.