ReviewDevelopmental neurobiology2018
Bad wrap: Myelin and myelin plasticity in health and disease.
Review in Developmental neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 91 citations in OpenAlex.
- Article
- From cellular diversity to coordinating nervous system function: the next frontier in non-neuronal cell biology.Frontiers in cellular neuroscience · 2026Article
- Alterations of multilayer network correlated with cognitive impairment and gene expression profiles in children with idiopathic generalized epilepsy.Scientific reports · 2025Article
- Tumor-related epilepsy in glioma: A multidisciplinary overview.Epilepsia · 2025Review
- Novel Animal Models for Multiple Sclerosis: R-Ras GTPases in Myelin Pathophysiology.Biomolecules · 2025Review
- Neuroplasticity in Post-Traumatic Stress Disorder.Revista de neurologia · 2025Review
- Whole-brain white matter variation across childhood environments.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Characterisation of GPR17-expressing oligodendrocyte precursors in human ischaemic lesions and correlation with reactive glial responses.The Journal of pathology · 2025Article
- Integrated Proteomics and Protein Co-expression Network Analysis Identifies Novel Epileptogenic Mechanism in Mesial Temporal Lobe Epilepsy.Molecular neurobiology · 2024Article
- Associations of depression and perceived physical fatigability with white matter integrity in older adults.Psychiatry research. Neuroimaging · 2024Article
- Identification of candidate biomarkers for GBM based on WGCNA.Scientific reports · 2024Article
- Heterogeneous patterning of blood-brain barrier and adaptive myelination as renewing key in gray and white matter.Neural regeneration research · 2024Article
- Role of transforming growth factor-β in peripheral nerve regeneration.Neural regeneration research · 2024Review
- Beyond the symptom: the biology of fatigue.Sleep · 2023Review
- Long-term benefits of mindfulness on white matter tracts underlying the cortical midline structures in panic disorder: A 2-year longitudinal study.Psychiatry and clinical neurosciences · 2023Article
- Article
- Epilepsy geneiScience · 2023Article
- DUSP15 expression is reduced in the hippocampus of Myrf knock-out mice but attention and object recognition memory remain intact.PloS one · 2023Article
- The human brain connectome weighted by the myelin content and total intra-axonal cross-sectional area of white matter tracts.Network neuroscience (Cambridge, Mass.) · 2023Article
- Circadian Control of Glial Cell Homeodynamics.Journal of biological rhythms · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Human central nervous system myelin development extends well into the fourth decade of life, and this protracted period underscores the potential for experience to modulate myelination. The concept of myelin plasticity implies adaptability in myelin structure and function in response to experiences during development and beyond. Mounting evidence supports this concept of neuronal activity-regulated changes in myelin-forming cells, including oligodendrocyte precursor cell proliferation, oligodendrogenesis and modulation of myelin microstructure. In healthy individuals, myelin plasticity in associative white matter structures of the brain is implicated in learning and motor function in both rodents and humans. Activity-dependent changes in myelin-forming cells may influence the function of neural networks that depend on the convergence of numerous neural signals on both a temporal and spatial scale. However, dysregulation of myelin plasticity can disadvantageously alter myelin microstructure and result in aberrant circuit function or contribute to pathological cell proliferation. Emerging roles for myelin plasticity in normal neurological function and in disease are discussed. © 2017 Wiley Periodicals, Inc. Develop Neurobiol 78: 123-135, 2018.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.