Evidence map›Paper›PMID 28986933›Full record

ArticleMedical physics2017

Liquid tissue surrogates for X-ray and CT phantom studies.

Paul F FitzGerald, Robert E Colborn, Peter M Edic, Jack W Lambert, Peter J Bonitatibus, Benjamin M Yeh

Open access · bronzeAbstract read
In one paragraph

Article in Medical physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  8. Lower limit of iron quantification using dual-energy CT - a phantom study.Journal of applied clinical medical physics · 2021
    Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Paul F FitzGeraldImaging, GE Global Research, 1 Research Circle, Niskayuna, NY, 12309, USA.
Robert E ColbornImaging, GE Global Research, 1 Research Circle, Niskayuna, NY, 12309, USA.
Peter M EdicImaging, GE Global Research, 1 Research Circle, Niskayuna, NY, 12309, USA.
Jack W LambertDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA.
Peter J BonitatibusImaging, GE Global Research, 1 Research Circle, Niskayuna, NY, 12309, USA.
Benjamin M YehDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143, USA.
GE Global Research (United States) · USUniversity of California System · US

Funding

Nanoparticle CT Contrast Agents for Reduced Radiation Dose and New Imaging ApplicR01EB015476 · NIBIB · GENERAL ELECTRIC GLOBAL RESEARCH CTR · PI EDIC, PETER, YEH, BENJAMIN M · 2013 to 2016
$3.4M
NIBIB NIH HHS R01 EB015476
6 · The paper itself

Abstract

purposeTo develop a simple method for producing liquid-tissue-surrogate (LTS) materials that accurately represent human soft tissues in terms of density and X-ray attenuation coefficient. METHODS AND MATERIALS: We evaluated hypothetical mixtures of water, glycerol, butanol, methanol, sodium chloride, and potassium nitrate; these mixtures were intended to emulate human adipose, blood, brain, kidney, liver, muscle, pancreas, and skin. We compared the hypothetical densities, effective atomic numbers (Z

resultsThe predicted densities, Z

conclusionOur method for formulating tissue surrogates allowed straightforward production of solutions with CT attenuation that closely matched the target tissues' expected CT attenuation values and trends with kVp. The LTSs' inexpensive and widely available constituent chemicals, combined with their liquid state, should enable rapid production and versatile use among different phantom and experiment types. Further study is warranted, such as the inclusion of contrast agents. These liquid tissue surrogates may potentially accelerate development and testing of advanced CT imaging techniques and technologies.

Indexed as

Phantoms, ImagingImage Processing, Computer-AssistedTomography, X-Ray Computedcomputed tomographyCTphantomstissue equivalentsX-ray

Identifiers

PMID28986933
PMCPMC5734616
OpenAlexW2762950427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.