ArticleAnnals of intensive care2017
Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis.
Article in Annals of intensive care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Systematic review of the relationship between comorbidity and out-of-hospital cardiac arrest outcomes.BMJ open · 2019Pooled it
- Beyond cardiac risk factors: non-cardiovascular comorbidities in sudden cardiac death prediction.Frontiers in cardiovascular medicine · 2026Review
- Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury.EMBO molecular medicine · 2024Article
- Intensive care unit cardiac arrest among very elderly critically ill patients - is cardiopulmonary resuscitation justified?Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Article
- Critical care outcomes in decompensated cirrhosis: a United States national inpatient sample cross-sectional study.Critical care (London, England) · 2024Article
- Can Blood Ammonia Level, Prehospital Time, and Return of Spontaneous Circulation Predict Neurological Outcomes of Out-of-Hospital Cardiac Arrest Patients? A Nationwide, Retrospective Cohort Study.Journal of clinical medicine · 2022Article
- Palliative Care in the Patient With Acute-on-Chronic Liver Failure.Clinical liver disease · 2022Review
- Impact of liver cirrhosis on ST-elevation myocardial infarction related shock and interventional management, a nationwide analysis.World journal of hepatology · 2022Article
- Outcomes of cirrhotic patients admitted to the intensive care unit after a successful cardiac arrest resuscitation.Saudi medical journal · 2021Article
- Characteristics and Risk Factors for Intensive Care Unit Cardiac Arrest in Critically Ill Patients with COVID-19-A Retrospective Study.Journal of clinical medicine · 2021Article
- In-Hospital Outcomes of Patients With Pulmonary Hypertension and Cirrhosis: A 6-Year Population Cohort Study of Over One Million Patients.Cardiology and therapy · 2020Article
- In-hospital cardiopulmonary resuscitation of patients with cirrhosis: A population-based analysis.PloS one · 2019Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrgan failure increases mortality in patients with liver cirrhosis. Data about resuscitated cardiac arrest patients with liver cirrhosis are missing. This study aims to assess aetiology, survival and functional outcome in patients after successful cardiopulmonary resuscitation (CPR) with and without liver cirrhosis.
methodsAnalysis of prospectively collected cardiac arrest registry data of consecutively hospital-admitted patients following successful CPR was performed. Patient's characteristics, admission diagnosis, severity of disease, course of disease, short- and long-term mortality as well as functional outcome were assessed and compared between patients with and without cirrhosis.
resultsOut of 1068 patients with successful CPR, 47 (4%) had liver cirrhosis. Acute-on-chronic liver failure (ACLF) was present in 33 (70%) of these patients on admission, and four patients developed ACLF during follow-up. Mortality at 1 year was more than threefold increased in patients with liver cirrhosis (OR 3.25; 95% CI 1.33-7.96). Liver cirrhosis was associated with impaired neurological outcome (OR for a favourable cerebral performance category: 0.13; 95% CI 0.04-0.36). None of the patients with Child-Turcotte-Pugh (CTP) C cirrhosis survived 28 days with good neurological outcome. Overall nine (19%) patients with cirrhosis survived 28 days with good neurological outcome. All patients with ACLF grade 3 died within 28 days.
conclusionCardiac arrest survivors with cirrhosis have worse outcome than those without. Although one quarter of patients with liver cirrhosis survived longer than 28 days after successful CPR, patients with CTP C as well as advanced ACLF did not survive 28 days with good neurological outcome.
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