Evidence map›Paper›PMID 28986852›Full record

ArticleAnnals of intensive care2017

Effect of inspiratory synchronization during pressure-controlled ventilation on lung distension and inspiratory effort.

Nuttapol Rittayamai, François Beloncle, Ewan C Goligher, Lu Chen, Jordi Mancebo, Jean-Christophe M Richard, Laurent Brochard

2 registry-linked trialsAbstract read
In one paragraph

Article in Annals of intensive care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05802745 completednot on this mapstarted 2023, after this paper: background citation

Airway Occlusion Pressure (P0.1) to Predict Extubation Failure in Critically Ill Patients: A Prospective Cohort Study

TypeobservationalSponsorCleveland Clinic Abu DhabiRan2023 to 2025Enrolled120ConditionsWeaning Failure, Mechanical Ventilation, Critically IllArmsReintubation
NCT06203405 narecruitingnot on this mapstarted 2023, after this paper: background citation

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

TypeinterventionalSponsorSiriraj HospitalRan2023 to 2026Enrolled214ConditionsRespiratory Failure, Critical Illness, Respiratory Distress Syndrome, Adult, Lung InjuryArmsTitrating sedation targeting both optimal P0.1 and appropriate arousal level, Fentanyl, Midazolam, Propofol, Dexmedetomidine
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nuttapol RittayamaiInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
François BeloncleInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Ewan C GoligherInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Lu ChenInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Jordi ManceboCentre de recherche du Centre Hospitalier de l, Université de Montréal (CRCHUM), University of Montreal', Montreal, Canada.
Jean-Christophe M RichardEmergency Department, General Hospital of Annecy, Annecy, France.
Laurent BrochardInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. BrochardL@smh.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn pressure-controlled (PC) ventilation, tidal volume (V

methodsProspective, randomized, crossover physiologic study performed in 14 spontaneously breathing mechanically ventilated patients recovering from acute respiratory failure (1 subsequently withdrew). PC modes were fully (PC-CMV), partially (PC-SIMV), and non-synchronized (PC-IMV using airway pressure release ventilation) and were applied randomly; driving pressure, inspiratory time, and set respiratory rate being similar for all modes. Airway, esophageal pressure, P

resultsV

conclusionsNon-synchronized PC mode lowers V

Indexed as

Airway pressure release ventilationLung-protective ventilationSpontaneous ventilationTranspulmonary pressureVentilator-induced lung injury

Identifiers

PMID28986852
PMCPMC5630544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.