ReviewInsights into imaging2017
Detector-based spectral CT with a novel dual-layer technology: principles and applications.
Review in Insights into imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
151 citing papers in PubMed, 276 citations in OpenAlex.
- Feasibility of reducing the contrast dose in infants and children with complex congenital heart disease using virtual monoenergetic images on dual-layer spectral detector computed tomography.Pediatric radiology · 2026Trial
- Preoperative predicting invasiveness of lung adenocarcinoma manifesting as ground-glass nodules based on multimodal images of dual-layer spectral detector CT radiomics models.Journal of cancer research and clinical oncology · 2023Trial
- Trial
- Spectral CT-based radiomics signature for distinguishing malignant pulmonary nodules from benign.BMC cancer · 2023Trial
- Radiomics analysis of dual-layer spectral detector CT-derived iodine density maps for predicting the pathological complete response of esophageal squamous cell carcinoma after neoadjuvant chemoimmunotherapy.European journal of radiology open · 2026Article
- Carotid atherosclerotic plaque characterization using dual-energy computed tomography angiography and its correlation with cerebral ischemic stroke.Quantitative imaging in medicine and surgery · 2026Article
- Dual-Layer Spectral CT for Locoregional Assessment of Rectal Cancer: A Comparison with MRI in a Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- Spectral CT-based Nomogram for Noninvasive Assessment and Prognostic Prediction of MSI/dMMR in Esophagogastric Junction Adenocarcinoma.Radiology. Imaging cancer · 2026Article
- Spectral computed tomography multi-parameter images for differentiating between tumor tissue and inflammatory tissue in pneumonic-type lung carcinoma lesions.Quantitative imaging in medicine and surgery · 2026Article
- Development and validation of a nomogram based on three-dimensional quantitative parameters from dual-layer detector spectral computed tomography for predicting treatment response to neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma.Journal of gastrointestinal oncology · 2026Article
- Performance of dual-layer spectral CT-based extracellular volume fraction to assess Ki-67 proliferation status in rectal cancer: comparison with diffusion kurtosis imaging.Insights into imaging · 2026Article
- Dual energy CT of pediatric genitourinary disorders.Abdominal radiology (New York) · 2026Review
- Theoretical modeling and performance analysis of a direct-indirect dual-layer flat-panel detector for contrast-enhanced breast imaging.Medical physics · 2026Article
- Dual-layer spectral CT for predicting spread through air spaces in lung adenocarcinoma: a dual-center study.European radiology · 2026Article
- Reducing Stent-Induced Blooming Artifacts Using Virtual Monoenergetic Imaging Reconstructions in a Superficial Femoral Artery Phantom: An In-Vitro Study.Cardiovascular engineering and technology · 2026Article
- The value of dual-layer detector spectral CT multiparameter imaging in distinguishing between benign lesions and carcinomas of the larynx and hypopharynx.Quantitative imaging in medicine and surgery · 2026Article
- Role of spectral CT in quantitative evaluation of pathologic response to neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma: a pilot study.Journal of translational medicine · 2026Article
- Radiomics analysis of energy CT-derived iodine density maps for predicting lymph node metastasis in colorectal cancer.Quantitative imaging in medicine and surgery · 2026Article
- An evaluation of dual-layer detector spectral CT for the estimation of MRI proton density fat fraction of the liver.Quantitative imaging in medicine and surgery · 2026Article
- Refining imaging parameters for dual-energy cone-beam computed tomography in image-guided radiation therapy.Journal of applied clinical medical physics · 2026Article
91 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detector-based spectral computed tomography is a novel dual-energy CT technology that employs two layers of detectors to simultaneously collect low- and high-energy data in all patients using standard CT protocols. In addition to the conventional polyenergetic images created for each patient, projection-space decomposition is used to generate spectral basis images (photoelectric and Compton scatter) for creating multiple spectral images, including material decomposition (iodine-only, virtual non-contrast, effective atomic number) and virtual monoenergetic images, on-demand according to clinical need. These images are useful in multiple clinical applications, including- improving vascular contrast, improving lesion conspicuity, decreasing artefacts, material characterisation and reducing radiation dose. In this article, we discuss the principles of this novel technology and also illustrate the common clinical applications. Teaching points • The top and bottom layers of dual-layer CT absorb low- and high-energy photons, respectively.• Multiple spectral images are generated by projection-space decomposition.• Spectral images can be generated in all patients scanned in this scanner.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.