Evidence map›Paper›PMID 28986730›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2018

Acute hantavirus infection presenting as haemolytic-uraemic syndrome (HUS): the importance of early clinical diagnosis.

J Clement, A P K Lee, G A Verpooten, L Laenen, V Vergote, H De Samblanx, Z N Berneman, M Van Ranst, P Maes

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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

J ClementNational Reference Laboratory for Hantavirus Infections, University Hospitals Leuven, Leuven, Belgium. jan.clement@uzleuven.be.
A P K LeeDepartment of Nephrology, Antwerp University Hospital, Edegem, Belgium.
G A VerpootenDepartment of Nephrology, Antwerp University Hospital, Edegem, Belgium.
L LaenenNational Reference Laboratory for Hantavirus Infections, University Hospitals Leuven, Leuven, Belgium.
V VergoteNational Reference Laboratory for Hantavirus Infections, University Hospitals Leuven, Leuven, Belgium.
H De SamblanxDepartment of Haematology, Antwerp University Hospital, Edegem, Belgium.
Z N BernemanDepartment of Haematology, Antwerp University Hospital, Edegem, Belgium.
M Van RanstNational Reference Laboratory for Hantavirus Infections, University Hospitals Leuven, Leuven, Belgium.
P MaesNational Reference Laboratory for Hantavirus Infections, University Hospitals Leuven, Leuven, Belgium.
Antwerp University Hospital · BEKU Leuven · BERega Institute for Medical Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European prototype of hantavirus, Puumala virus (PUUV), isolated from a common wild rodent, the bank vole (Myodes glareolus), causes nephropathia epidemica (NE). NE can perfectly mimic haemolytic-uraemic syndrome (HUS), progressing from an aspecific flu-like syndrome to acute kidney injury with thrombocytopaenia, and presenting with some signs of haemolytic anaemia and/or coagulopathy. Moreover, both NE and HUS can occur in local outbreaks. We report an isolated case of NE, initially referred for plasmapheresis for suspected HUS, although signs of overt haemolysis were lacking. Early suspicion of hantavirus infection, later confirmed by serology and reverse transcription polymerase chain reaction (RT-PCR), prevented subsequent excessive treatment modalities.

Indexed as

Acute Kidney InjuryAnimalsArvicolinaeDiagnosis, DifferentialHemolytic-Uremic SyndromeHemorrhagic Fever with Renal SyndromeHumansMaleMiddle AgedPuumala virusRodent DiseasesThrombocytopenia

Identifiers

PMID28986730
OpenAlexW2761331832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.