Evidence map›Paper›PMID 28986445›Full record

ArticleGenetics2017

Histone H3 Threonine 11 Phosphorylation Is Catalyzed Directly by the Meiosis-Specific Kinase Mek1 and Provides a Molecular Readout of Mek1 Activity

Ryan Kniewel, Hajime Murakami, Yan Liu, Masaru Ito, Kunihiro Ohta, Nancy M Hollingsworth, Scott Keeney

Open access · greenAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Histone modification inComputational and structural biotechnology journal · 2023
    Review
  8. Article
  9. Article
  10. Chromosome architecture and homologous recombination in meiosis.Frontiers in cell and developmental biology · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Phospho-Regulation of Meiotic Prophase.Frontiers in cell and developmental biology · 2021
    Review
  15. Article
  16. When histones are under glucose starvation.Journal of biosciences · 2020
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Ryan KniewelMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065.ORCID 0000-0003-3462-6450
Hajime MurakamiMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065.ORCID 0000-0002-7022-6887
Yan LiuDepartment of Biochemistry and Cell Biology, Stony Brook University, New York 11794.
Masaru ItoDepartment of Life Sciences, The University of Tokyo, 153-8902, Japan.
Kunihiro OhtaDepartment of Life Sciences, The University of Tokyo, 153-8902, Japan.
Nancy M HollingsworthDepartment of Biochemistry and Cell Biology, Stony Brook University, New York 11794.ORCID 0000-0003-3300-6444
Scott KeeneyMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065 s-keeney@ski.mskcc.org.ORCID 0000-0002-1283-6417
Memorial Sloan Kettering Cancer Center · USStony Brook University · USCornell University · USThe University of Tokyo · JP

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
ANALYSIS OF MEIOTIC CHROMOSOME SYNAPSIS IN YEASTR01GM050717 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI HOLLINGSWORTH, NANCY M. · 1995 to 2020
$8.0M
Mechanism and regulation of meiotic recombinationR35GM118092 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Scott Keeney · 2016 to 2026
$7.0M
Mechanism of meiotic recombination in yeastR01GM058673 · NIGMS · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI KEENEY, SCOTT · 1999 to 2015
$6.0M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R01 GM050717NIGMS NIH HHS R01 GM058673NIGMS NIH HHS R35 GM118092
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell Cycle ProteinsChromosomes, FungalDNA-Binding ProteinsDNA Breaks, Double-StrandedHistonesMAP Kinase Kinase 1MeiosisMutationPhosphorylationRad51 RecombinaseRecombination, GeneticSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSporesThreonineCell Cycle ProteinsDMC1 protein, S cerevisiaeDNA-Binding ProteinsHistonesHOP1 protein, S cerevisiaeMAP Kinase Kinase 1RAD51 protein, S cerevisiaeRad51 RecombinaseRED1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsThreonineChromosome structureDNA damage responseHistone phosphorylationMeiosisMek1

Identifiers

PMID28986445
PMCPMC5714450
OpenAlexW2950062819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.