ArticleDiabetes2017
Objectively Measured Physical Activity, Sedentary Behavior, and Genetic Predisposition to Obesity in U.S. Hispanics/Latinos: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
Article in Diabetes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Polygenic scores and physical fitness prediction: a systematic review.Human genetics · 2026Pooled it
- Interactions between genetic and lifestyle factors on cardiometabolic disease-related outcomes in Latin American and Caribbean populations: A systematic review.Frontiers in nutrition · 2023Pooled it
- Polygenic risk score for obesity and the quality, quantity, and timing of workplace food purchases: A secondary analysis from the ChooseWell 365 randomized trial.PLoS medicine · 2020Trial
- Movement- and Posture-based Measures of Sedentary Patterns and Associations with Metabolic Syndrome in Hispanic/Latino and non-Hispanic Adults.Journal of racial and ethnic health disparities · 2025Article
- Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review.HGG advances · 2025Review
- Physical activity alters the effect of genetic determinants of adiposity on hypertension among individuals of European ancestry in the UKB.Scandinavian journal of medicine & science in sports · 2024Article
- Impact of polygenic score for BMI on weight loss effectiveness and genome-wide association analysis.International journal of obesity (2005) · 2024Observational
- Long-term drinking of green tea combined with exercise improves hepatic steatosis and obesity in male mice induced by high-fat diet.Food science & nutrition · 2024Article
- Evolving Science on Cardiovascular Disease Among Hispanic/Latino Adults: JACC International.Journal of the American College of Cardiology · 2023Review
- Obesity among Latinx people in the United States: A review.Obesity (Silver Spring, Md.) · 2023Review
- Latino Children's Obesity Risk Varies by Place of Birth: Findings from New York City Public School Youth, 2006-2017.Childhood obesity (Print) · 2022Observational
- Association of Alcohol Use and Physical Activity with Body Mass Index in Mexican-Origin Adults.Journal of racial and ethnic health disparities · 2022Article
- Joint associations of peripheral artery disease and accelerometry-based physical activity with mortality: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL).Atherosclerosis · 2022Article
- Synergizing Mouse and Human Studies to Understand the Heterogeneity of Obesity.Advances in nutrition (Bethesda, Md.) · 2021Review
- Physical Activity, Obesity, and Hypertension among Adults in a Rapidly Urbanised City.International journal of hypertension · 2021Article
- Central Obesity, Cardiometabolic Risk, and Cognitive Change in the Study of Latinos - Investigation of Neurocognitive Aging.Journal of Alzheimer's disease : JAD · 2021Article
- Accelerometer-assessed physical activity and incident diabetes in a population covering the adult life span: the Hispanic Community Health Study/Study of Latinos.The American journal of clinical nutrition · 2020Article
- Evaluation of the Predictive Ability, Environmental Regulation and Pharmacogenetics Utility of a BMI-Predisposing Genetic Risk Score during Childhood and Puberty.Journal of clinical medicine · 2020Article
- Dietary supplement of Yunkang 10 green tea and treadmill exercise ameliorate high fat diet induced metabolic syndrome of C57BL/6 J mice.Nutrition & metabolism · 2020Article
- Neighborhoods to Nucleotides - Advances and gaps for an obesity disparities systems epidemiology model.Current epidemiology reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 1 country.
Funding
Abstract
Studies using self-reported data suggest a gene-physical activity interaction on obesity, yet the influence of sedentary behavior, distinct from a lack of physical activity, on genetic associations with obesity remains unclear. We analyzed interactions of accelerometer-measured moderate to vigorous physical activity (MVPA) and time spent sedentary with genetic variants on obesity among 9,645 U.S. Hispanics/Latinos. An overall genetic risk score (GRS), a central nervous system (CNS)-related GRS, and a non-CNS-related GRS were calculated based on 97 BMI-associated single nucleotide polymorphisms (SNPs). Genetic association with BMI was stronger in individuals with lower MVPA (first tertile) versus higher MVPA (third tertile) (β = 0.78 kg/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.