Evidence map›Paper›PMID 28985907›Full record

ArticleFertility and sterility2017

Association between preconception maternal beverage intake and in vitro fertilization outcomes.

Ronit Machtinger, Audrey J Gaskins, Abdallah Mansur, Michal Adir, Catherine Racowsky, Andrea A Baccarelli, Russ Hauser, Jorge E Chavarro

Open access · bronzeAbstract read
In one paragraph

Article in Fertility and sterility, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Development of a nutrition screening tool to identify need for dietetic intervention in female infertility.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023
    Review
  9. Article
  10. Observational
  11. Review
  12. Article
  13. Can Nutrition Help in the Treatment of Infertility?Preventive nutrition and food science · 2021
    Review
  14. Relationship between nutrition and reproduction.Reproductive medicine and biology · 2020
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ronit MachtingerSheba Medical Center, Ramat-Gan and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: Ronit.Machtinger@sheba.health.gov.il.
Audrey J GaskinsDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Abdallah MansurSheba Medical Center, Ramat-Gan and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Michal AdirSheba Medical Center, Ramat-Gan and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Catherine RacowskyBrigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Andrea A BaccarelliEnvironmental Precision Biosciences Laboratory, Columbia University, Mailman School of Public Health, New York, New York.
Russ HauserDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Jorge E ChavarroDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Brigham and Women's Hospital · USTel Aviv University · ILColumbia University · USHarvard University · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI HU, FRANK B · 1992 to 2021
$25.0M
Environmental Chemicals, Exosomal miRNAs in Ovarian Follicles, and IVF SuccessR21ES024236 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI HAUSER, RUSS B · 2014 to 2015
$470k
Maternal Exposure to Air Pollution and Early Pregnancy OutcomesK99ES026648 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI GASKINS, AUDREY JANE · 2017 to 2018
$246k
NICHD NIH HHS L50 HD085359NIDDK NIH HHS P30 DK046200NIEHS NIH HHS K99 ES026648NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R21 ES024236
6 · The paper itself

Abstract

objectiveTo study whether maternal intake of beverage type affects IVF outcomes.

designA prospective study.

settingTertiary, university-affiliated center. PATIENT(S): Three hundred forty women undergoing IVF from 2014 through 2016 for infertility as well as for pregenetic diagnosis for autosomal recessive diseases were enrolled during ovarian stimulation and completed a questionnaire describing their usual beverage consumption. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): IVF outcomes were abstracted from medical records. Total caffeine intake was estimated by summing the caffeine content for specific beverages multiplied by frequency of intake. Associations between specific types of beverages and IVF outcomes were analyzed using Poisson and logistic regression models adjusting for possible confounders. RESULT(S): Higher intake of sugared soda was associated with lower total, mature, and fertilized oocytes and top-quality embryos after ovarian stimulation. Women who consumed sugared soda had, on average, 1.1 fewer oocytes retrieved, 1.2 fewer mature oocytes retrieved, 0.6 fewer fertilized oocytes, and 0.6 fewer top-quality embryos compared with women who did not consume sugared soda. Furthermore, compared with women who did not drink sugared soda, the adjusted difference in percent of cycles resulting in live birth for women consuming 0.1-1 cups/day and >1 cup/day were -12% and -16%, respectively. No associations were found between consumption of coffee, caffeine, or diet sodas and IVF outcome. CONCLUSION(S): Sugared beverages, independent of their caffeine content, may be a bigger threat to reproductive success than caffeine and caffeinated beverages without added sugar.

Indexed as

Carbonated BeveragesCoffeeFertilityFertilization in VitroMaternal Nutritional Physiological PhenomenaAdultBlastocystCaffeineChi-Square DistributionFemaleHabitsHumansInfertilityIn Vitro Oocyte Maturation TechniquesLogistic ModelsMultivariate AnalysisCaffeineCoffeecaffeinated beveragesIVFnon-caffeinated beveragessugared soda

Identifiers

PMID28985907
PMCPMC5716855
OpenAlexW2763298452

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.